Sleep Pharmacogenetics: The Promise of Precision Medicine.

Journal Article (Journal Article;Review)

Pharmacogenetics is the branch of personalized medicine concerned with the variability in drug response occurring because of heredity. Advances in genetics research, and decreasing costs of gene sequencing, are promoting tremendous growth in pharmacogenetics in all areas of medicine, including sleep medicine. This article reviews the body of research indicating that there are genetic variations that affect the therapeutic actions and adverse effects of agents used for the treatment of sleep disorders to show the potential of pharmacogenetics to improve the clinical practice of sleep medicine.

Full Text

Duke Authors

Cited Authors

  • Krystal, AD; Prather, AA

Published Date

  • September 2019

Published In

Volume / Issue

  • 14 / 3

Start / End Page

  • 317 - 331

PubMed ID

  • 31375201

Electronic International Standard Serial Number (EISSN)

  • 1556-4088

Digital Object Identifier (DOI)

  • 10.1016/j.jsmc.2019.05.003


  • eng

Conference Location

  • United States