Fluorinated copolymer nanoparticles for multimodal imaging applications
Journal Article (Journal Article)
Nanomaterials have emerged as valuable tools in biomedical imaging techniques. Here, the synthesis and characterization of a novel fluorinated nanoparticle with potential applications as an MRI contrast agent is reported. Particles were synthesized using a free radical polymer-ízation technique. Secondary ion mass spectrometry analysis showed that the particles' surface contained fluorinated groups and nitrogen-containing groups. Solid-state NMR spectroscopy suggested the presence of two distinct fluorine resonances, which conforms to the structure of the fluorinated monomer. Ongoing studies aim to evaluate the performance of the nanoparticles as MRI contrast agents both in vitro and in vivo. © 2010 WILEY-VCH Verlag GmbH & Co. KGaA,.
Full Text
Duke Authors
Cited Authors
- Bailey, MM; Mahoney, CM; Dempah, KE; Davis, JM; Becker, ML; Khondee, S; Munson, EJ; Berkland, C
Published Date
- January 4, 2010
Published In
Volume / Issue
- 31 / 1
Start / End Page
- 87 - 92
Electronic International Standard Serial Number (EISSN)
- 1521-3927
International Standard Serial Number (ISSN)
- 1022-1336
Digital Object Identifier (DOI)
- 10.1002/marc.200900505
Citation Source
- Scopus