Pragmatic clinical trials offer unique opportunities for disseminating, implementing, and sustaining evidence-based practices into clinical care: Proceedings of a workshop.

Conference Paper

The National Institutes of Health (NIH) Health Care Systems (HCS) Research Collaboratory hosted a workshop to explore challenges and strategies for the dissemination, implementation, and sustainability of findings from pragmatic clinical trials (PCTs) embedded in HCS. PCTs are designed to assess the impact of interventions delivered in usual or real-world conditions and leverage existing infrastructure to answer important clinical questions. The goal of the workshop was to discuss strategies for conducting impactful future PCTs that bridge the gap between evidence, practice, and policy. This paper summarizes presentations about how to design and conduct PCTs embedded in HCS and use dissemination and implementation strategies during the planning and conduct of projects, emphasizing the ever-changing world of care delivery and the need for pragmatic trial operations to adapt at various levels of operation.

Full Text

Duke Authors

Cited Authors

  • Tuzzio, L; Larson, EB; Chambers, DA; Coronado, GD; Curtis, LH; Weber, WJ; Zatzick, DF; Meyers, CM

Published Date

  • March 2019

Published In

Volume / Issue

  • 7 / 1

Start / End Page

  • 51 - 57

PubMed ID

  • 30594497

Pubmed Central ID

  • PMC6557660

Electronic International Standard Serial Number (EISSN)

  • 2213-0772

Digital Object Identifier (DOI)

  • 10.1016/j.hjdsi.2018.12.003

Conference Location

  • Netherlands