Skip to main content
Journal cover image

The International Atomic Energy Agency International Doubly Labelled Water Database: Aims, Scope and Procedures.

Publication ,  Journal Article
Speakman, JR; Pontzer, H; Rood, J; Sagayama, H; Schoeller, DA; Westerterp, KR; Wong, WW; Yamada, Y; Loechl, C; Murphy-Alford, AJ
Published in: Annals of nutrition & metabolism
January 2019

The doubly labelled water (DLW) method is an isotope-based technique that quantifies total energy expenditure (TEE) over periods of 1-3 weeks from the differential elimination of stable isotopes of oxygen and hydrogen. The method was invented in the 1950s, but limited ability to measure low isotope enrichments combined with the high cost of isotopes meant it only became feasible to use in humans in the 1980s. It is still relatively expensive to use, and alone small samples are unable to tackle some of the important questions surrounding energy balance such as how have expenditures changed over time and how do expenditures differ with age, between sexes and in different environments?By combining information across studies, answers to such questions may be possible. The International Atomic Energy Agency (IAEA) DLW database was established to pool DLW data across multiple studies. It was initiated by the main labs currently using the method and is hosted by the IAEA. At present, the database contains 6,621 measures of TEE by DLW from individuals in 23 countries, along with various additional data on the study participants. Key Messages: The IAEA DLW database is a key resource enabling future studies of energy demands.

Duke Scholars

Published In

Annals of nutrition & metabolism

DOI

EISSN

1421-9697

ISSN

0250-6807

Publication Date

January 2019

Volume

75

Issue

2

Start / End Page

114 / 118

Related Subject Headings

  • Water Supply
  • Pregnancy
  • Pediatrics
  • Oxygen Isotopes
  • Overnutrition
  • Nutrition & Dietetics
  • Malnutrition
  • Male
  • International Agencies
  • Infant
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Speakman, J. R., Pontzer, H., Rood, J., Sagayama, H., Schoeller, D. A., Westerterp, K. R., … Murphy-Alford, A. J. (2019). The International Atomic Energy Agency International Doubly Labelled Water Database: Aims, Scope and Procedures. Annals of Nutrition & Metabolism, 75(2), 114–118. https://doi.org/10.1159/000503668
Journal cover image

Published In

Annals of nutrition & metabolism

DOI

EISSN

1421-9697

ISSN

0250-6807

Publication Date

January 2019

Volume

75

Issue

2

Start / End Page

114 / 118

Related Subject Headings

  • Water Supply
  • Pregnancy
  • Pediatrics
  • Oxygen Isotopes
  • Overnutrition
  • Nutrition & Dietetics
  • Malnutrition
  • Male
  • International Agencies
  • Infant