Cancer in adolescents and young adults: treatment and outcome in Victoria.

Journal Article (Journal Article)

OBJECTIVES: To describe the location of treatment, recruitment to clinical trials and outcomes for adolescents and young adults treated for cancer in Victoria. DESIGN AND SETTING: Retrospective review of all adolescents and young adults aged 10-24 years diagnosed with cancer between 1992 and 1996, identified from the Victorian Cancer Registry. MAIN OUTCOME MEASURES: Treatment regimen (clinical trial, treatment protocol or neither), compliance with treatment and 5-year survival. RESULTS: Questionnaires were completed for 576 of 665 eligible adolescents and young adults (87% response rate). Recruitment into clinical trials decreased with increasing age. Adolescents aged 10-19 years were more likely to be recruited to a clinical trial if treated at a paediatric hospital. For all cancers, 5-year survival was similar across the age groups and was not influenced by the place of treatment. Only 1% of adolescents and young adults failed to complete planned therapy due to non-compliance. CONCLUSIONS: Despite a similar incidence of cancer to that in younger children, adolescents and young adults with cancer are poorly recruited into clinical trials in Victoria. Establishment of a cancer resource network in Victoria may provide information to both paediatric and adult oncologists about currently available clinical trials.

Full Text

Duke Authors

Cited Authors

  • Mitchell, AE; Scarcella, DL; Rigutto, GL; Thursfield, VJ; Giles, GG; Sexton, M; Ashley, DM

Published Date

  • January 19, 2004

Published In

Volume / Issue

  • 180 / 2

Start / End Page

  • 59 - 62

PubMed ID

  • 14723585

International Standard Serial Number (ISSN)

  • 0025-729X

Digital Object Identifier (DOI)

  • 10.5694/j.1326-5377.2004.tb05799.x


  • eng

Conference Location

  • Australia