NAIP inflammasomes give the NOD to bacterial ligands.

Journal Article (Journal Article)

NLRs are innate immune sensors that monitor the sanctity of the cytosolic compartment. In a recent paper in Molecular Cell, Tenthorey et al. reveal a novel ligand-sensing interface within regions of the oligomerization domain of the NAIPs, rather than within the leucine-rich repeats, as was anticipated.

Full Text

Duke Authors

Cited Authors

  • Maltez, VI; Miao, EA

Published Date

  • November 2014

Published In

Volume / Issue

  • 35 / 11

Start / End Page

  • 503 - 504

PubMed ID

  • 25443492

Pubmed Central ID

  • 25443492

Electronic International Standard Serial Number (EISSN)

  • 1471-4981

International Standard Serial Number (ISSN)

  • 1471-4906

Digital Object Identifier (DOI)

  • 10.1016/j.it.2014.10.002

Language

  • eng