miniMAVS, You Complete Me!

Journal Article (Journal Article)

The functional significance of protein diversification through translational regulation in mammals is largely unexplored. Brubaker et al. now describe the generation of two functionally distinct mammalian proteins, MAVS and miniMAVS, from a single bicistronic mRNA and suggest that noncanonical translation may impact multiple players in innate immune regulation.

Full Text

Duke Authors

Cited Authors

  • Rayamajhi, M; Miao, EA; Moorman, NJ

Published Date

  • February 2014

Published In

Volume / Issue

  • 156 / 4

Start / End Page

  • 629 - 630

PubMed ID

  • 24529369

Pubmed Central ID

  • PMC5097455

Electronic International Standard Serial Number (EISSN)

  • 1097-4172

International Standard Serial Number (ISSN)

  • 0092-8674

Digital Object Identifier (DOI)

  • 10.1016/j.cell.2014.01.045

Language

  • eng