miniMAVS, You Complete Me!
Journal Article (Journal Article)
The functional significance of protein diversification through translational regulation in mammals is largely unexplored. Brubaker et al. now describe the generation of two functionally distinct mammalian proteins, MAVS and miniMAVS, from a single bicistronic mRNA and suggest that noncanonical translation may impact multiple players in innate immune regulation.
Full Text
Duke Authors
Cited Authors
- Rayamajhi, M; Miao, EA; Moorman, NJ
Published Date
- February 13, 2014
Published In
Volume / Issue
- 156 / 4
Start / End Page
- 629 - 630
PubMed ID
- 24529369
Pubmed Central ID
- PMC5097455
Electronic International Standard Serial Number (EISSN)
- 1097-4172
Digital Object Identifier (DOI)
- 10.1016/j.cell.2014.01.045
Language
- eng
Conference Location
- United States