The role of Sfrp and DKK proteins in cardiomyocyte development.
Publication
, Journal Article
Hsueh, Y-C; Hodgkinson, CP; Gomez, JA
Published in: Physiol Rep
February 2021
In this review, we summarize the role of Wnt proteins in cardiomyogenesis. More specifically, we focus on how the development of cardiomyocytes from precursor cells involves a complex interplay between Wnt canonical β-catenin signaling pathways and Wnt noncanonical signaling pathways involving PCP and JNK. We also describe recent literature which suggests that endogenous Wnt inhibitors such as the Sfrp and DKK proteins play important roles in regulating the cardiomyocyte differentiation.
Duke Scholars
Published In
Physiol Rep
DOI
EISSN
2051-817X
Publication Date
February 2021
Volume
9
Issue
3
Start / End Page
e14678
Location
United States
Related Subject Headings
- Wnt Signaling Pathway
- Regeneration
- Recovery of Function
- Phenotype
- Myocytes, Cardiac
- Morphogenesis
- Intercellular Signaling Peptides and Proteins
- Humans
- Heart Diseases
- Heart
Citation
APA
Chicago
ICMJE
MLA
NLM
Hsueh, Y.-C., Hodgkinson, C. P., & Gomez, J. A. (2021). The role of Sfrp and DKK proteins in cardiomyocyte development. Physiol Rep, 9(3), e14678. https://doi.org/10.14814/phy2.14678
Hsueh, Ying-Chang, Conrad P. Hodgkinson, and Jose A. Gomez. “The role of Sfrp and DKK proteins in cardiomyocyte development.” Physiol Rep 9, no. 3 (February 2021): e14678. https://doi.org/10.14814/phy2.14678.
Hsueh Y-C, Hodgkinson CP, Gomez JA. The role of Sfrp and DKK proteins in cardiomyocyte development. Physiol Rep. 2021 Feb;9(3):e14678.
Hsueh, Ying-Chang, et al. “The role of Sfrp and DKK proteins in cardiomyocyte development.” Physiol Rep, vol. 9, no. 3, Feb. 2021, p. e14678. Pubmed, doi:10.14814/phy2.14678.
Hsueh Y-C, Hodgkinson CP, Gomez JA. The role of Sfrp and DKK proteins in cardiomyocyte development. Physiol Rep. 2021 Feb;9(3):e14678.
Published In
Physiol Rep
DOI
EISSN
2051-817X
Publication Date
February 2021
Volume
9
Issue
3
Start / End Page
e14678
Location
United States
Related Subject Headings
- Wnt Signaling Pathway
- Regeneration
- Recovery of Function
- Phenotype
- Myocytes, Cardiac
- Morphogenesis
- Intercellular Signaling Peptides and Proteins
- Humans
- Heart Diseases
- Heart