Current Appointments & Affiliations
Associate Professor in Medicine
·
2023 - Present
Medicine, Cardiology,
Medicine
Associate Professor of Pathology
·
2023 - Present
Pathology,
Clinical Science Departments
Recent Publications
Nucleosome repositioning in cardiac reprogramming.
Journal Article PLoS One · 2025 Early events in the reprogramming of fibroblasts to cardiac muscle cells are unclear. While various histone undergo modification and re-positioning, and these correlate with the activity of certain genes, it is unknown if these events are causal or happen ... Full text Link to item CiteThe impact of aging on cardiac repair and regeneration.
Journal Article The Journal of biological chemistry · September 2024 In contrast to neonates and lower organisms, the adult mammalian heart lacks any capacity to regenerate following injury. The vast majority of our understanding of cardiac regeneration is based on research in young animals. Research in aged individuals is ... Full text CiteModifying miRs for effective reprogramming of fibroblasts to cardiomyocytes.
Journal Article Mol Ther Nucleic Acids · June 11, 2024 Reprogramming scar fibroblasts into cardiomyocytes has been proposed to reverse the damage associated with myocardial infarction. However, the limited improvement in cardiac function calls for enhanced strategies. We reported enhanced efficacy of our miR r ... Full text Link to item CiteRecent Grants
Enhancing cardiac reprogramming via TLR3
ResearchPrincipal Investigator · Awarded by Rosenfeld Heart Foundation · 2018 - 2024Integrated Cellular and Tissue Engineering for Ischemic Heart Disease
ResearchHealth Educator · Awarded by University of Alabama at Birmingham · 2016 - 2024Sfrp2 promotes cardiac regeneration via c-Kit(+) cell differentiation
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2018 - 2022View All Grants
Education, Training & Certifications
University of London (United Kingdom) ·
1996
Ph.D.