Receipt and predictors of smoking cessation pharmacotherapy among veterans with and without HIV.

Journal Article (Journal Article;Multicenter Study)

Smoking is highly prevalent among people living with HIV (PLWH) and increases cardiovascular risk. Pharmacotherapies such as nicotine replacement therapy (NRT), bupropion, and varenicline help to reduce smoking, though rates of receipt among PLWH compared with HIV-uninfected persons are unknown. Among 814 PLWH and 908 uninfected patients enrolled in the Veterans Aging Cohort Study (2012-2017) who reported current smoking, we used marginal multivariable log-linear regression models to estimate adjusted relative risks (ARR) of receiving pharmacotherapy by HIV status. We also assessed patient-level factors associated with pharmacotherapy receipt within each group. In multivariable analyses, receipt of NRT was less likely among PLWH relative to uninfected participants (ARR 0.77, 95% CI 0.67, 0.89). In both populations, documented mental health disorders and contemplation to quit were associated with greater likelihood of receiving pharmacotherapy. Further research is needed to explore potential treatment disparities.

Full Text

Duke Authors

Cited Authors

  • Shahrir, S; Crothers, K; McGinnis, KA; Chan, KCG; Baeten, JM; Wilson, SM; Butt, AA; Pisani, MA; Baldassarri, SR; Justice, A; Williams, EC

Published Date

  • 2020

Published In

Volume / Issue

  • 63 / 2

Start / End Page

  • 118 - 124

PubMed ID

  • 31987807

Pubmed Central ID

  • PMC7251937

Electronic International Standard Serial Number (EISSN)

  • 1873-1740

Digital Object Identifier (DOI)

  • 10.1016/j.pcad.2020.01.003


  • eng

Conference Location

  • United States