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New insights into the classification and nomenclature of cortical GABAergic interneurons.

Publication ,  Journal Article
DeFelipe, J; López-Cruz, PL; Benavides-Piccione, R; Bielza, C; Larrañaga, P; Anderson, S; Burkhalter, A; Cauli, B; Fairén, A; Feldmeyer, D ...
Published in: Nat Rev Neurosci
March 2013

A systematic classification and accepted nomenclature of neuron types is much needed but is currently lacking. This article describes a possible taxonomical solution for classifying GABAergic interneurons of the cerebral cortex based on a novel, web-based interactive system that allows experts to classify neurons with pre-determined criteria. Using Bayesian analysis and clustering algorithms on the resulting data, we investigated the suitability of several anatomical terms and neuron names for cortical GABAergic interneurons. Moreover, we show that supervised classification models could automatically categorize interneurons in agreement with experts' assignments. These results demonstrate a practical and objective approach to the naming, characterization and classification of neurons based on community consensus.

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Published In

Nat Rev Neurosci

DOI

EISSN

1471-0048

Publication Date

March 2013

Volume

14

Issue

3

Start / End Page

202 / 216

Location

England

Related Subject Headings

  • gamma-Aminobutyric Acid
  • Terminology as Topic
  • Neurology & Neurosurgery
  • Interneurons
  • Humans
  • Cluster Analysis
  • Cerebral Cortex
  • Bayes Theorem
  • Animals
  • Algorithms
 

Citation

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DeFelipe, J., López-Cruz, P. L., Benavides-Piccione, R., Bielza, C., Larrañaga, P., Anderson, S., … Ascoli, G. A. (2013). New insights into the classification and nomenclature of cortical GABAergic interneurons. Nat Rev Neurosci, 14(3), 202–216. https://doi.org/10.1038/nrn3444
DeFelipe, Javier, Pedro L. López-Cruz, Ruth Benavides-Piccione, Concha Bielza, Pedro Larrañaga, Stewart Anderson, Andreas Burkhalter, et al. “New insights into the classification and nomenclature of cortical GABAergic interneurons.Nat Rev Neurosci 14, no. 3 (March 2013): 202–16. https://doi.org/10.1038/nrn3444.
DeFelipe J, López-Cruz PL, Benavides-Piccione R, Bielza C, Larrañaga P, Anderson S, et al. New insights into the classification and nomenclature of cortical GABAergic interneurons. Nat Rev Neurosci. 2013 Mar;14(3):202–16.
DeFelipe, Javier, et al. “New insights into the classification and nomenclature of cortical GABAergic interneurons.Nat Rev Neurosci, vol. 14, no. 3, Mar. 2013, pp. 202–16. Pubmed, doi:10.1038/nrn3444.
DeFelipe J, López-Cruz PL, Benavides-Piccione R, Bielza C, Larrañaga P, Anderson S, Burkhalter A, Cauli B, Fairén A, Feldmeyer D, Fishell G, Fitzpatrick D, Freund TF, González-Burgos G, Hestrin S, Hill S, Hof PR, Huang J, Jones EG, Kawaguchi Y, Kisvárday Z, Kubota Y, Lewis DA, Marín O, Markram H, McBain CJ, Meyer HS, Monyer H, Nelson SB, Rockland K, Rossier J, Rubenstein JLR, Rudy B, Scanziani M, Shepherd GM, Sherwood CC, Staiger JF, Tamás G, Thomson A, Wang Y, Yuste R, Ascoli GA. New insights into the classification and nomenclature of cortical GABAergic interneurons. Nat Rev Neurosci. 2013 Mar;14(3):202–216.

Published In

Nat Rev Neurosci

DOI

EISSN

1471-0048

Publication Date

March 2013

Volume

14

Issue

3

Start / End Page

202 / 216

Location

England

Related Subject Headings

  • gamma-Aminobutyric Acid
  • Terminology as Topic
  • Neurology & Neurosurgery
  • Interneurons
  • Humans
  • Cluster Analysis
  • Cerebral Cortex
  • Bayes Theorem
  • Animals
  • Algorithms