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Josh Huang

Josh Huang

Duke School of Medicine Distinguished Professor in Neuroscience
Neurobiology
josh.huang@duke.edu
311 Research Drive, Box 3209, Durham, NC 27710
311 Research Drive, Box 3209, Durham, NC 27710

Overview

We study the development and function of cortical circuits underlying motor control and cognitive processing. Our research program integrates multi-faceted approaches from genetic engineering to single-cell genomics, developmental neurobiology, imaging, electrophysiology, and behavioral analyses, and aims to link fundamental neuroscience to the understanding and treatment of neuropsychiatric disorders.    

Current Appointments & Affiliations

Duke School of Medicine Distinguished Professor in Neuroscience · 2022 - Present Neurobiology, Basic Science Departments
Professor of Neurobiology · 2021 - Present Neurobiology, Basic Science Departments
Professor of Biomedical Engineering · 2021 - Present Biomedical Engineering, Pratt School of Engineering
Professor of Cell Biology · 2022 - Present Cell Biology, Basic Science Departments

In the News

Published October 5, 2022
New RNA-Based Tool Can Illuminate Brain Circuits, Edit Specific Cells
Published May 18, 2022
University Awards 24 New Distinguished Professorships
Published April 28, 2022
Four Faculty Elected to American Academy of Arts & Sciences

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Recent Publications

Orderly specification and precise laminar deployment of mouse cortical projection neuron types through intermediate progenitors.

Journal Article Dev Cell · March 7, 2025 The cerebral cortex comprises diverse types of glutamatergic projection neurons (PNs) generated from radial glial progenitors (RGs) through either direct neurogenesis (dNG) or indirect neurogenesis (iNG) via intermediate progenitors (IPs). A foundational c ... Full text Link to item Cite

CellREADR: An ADAR-based RNA sensor-actuator device.

Journal Article Methods Enzymol · 2025 RNAs are central mediators of genetic information flow and gene regulation that underlie diverse cell types and cell states across species. Thus, methods that can sense and respond to RNA profiles in living cells will have broad applications in biology and ... Full text Link to item Cite
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Recent Grants

Discovering the cell type basis of the IT projection system and its dysregulation after perinatal HIE

ResearchMentor · Awarded by National Institutes of Health · 2024 - 2029

Neurobiology Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2024 - 2029

Distal mRNA localization and translation in neural stem cells of the developing brain

ResearchCollaborator · Awarded by National Institutes of Health · 2018 - 2028

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Education, Training & Certifications

Brandeis University · 1995 Ph.D.

External Links

Huang Lab