Cardiovascular Health in Pediatric Rheumatologic Diseases.

Journal Article (Journal Article;Review)

Cardiovascular disease risk is evident during childhood for patients with juvenile systemic lupus erythematosus, juvenile dermatomyositis, and juvenile idiopathic arthritis. The American Heart Association defines cardiovascular health as a positive health construct reflecting the sum of protective factors against cardiovascular disease. Disease-related factors such as chronic inflammation and endothelial dysfunction increase cardiovascular disease risk directly and through bidirectional relationships with poor cardiovascular health factors. Pharmacologic and nonpharmacologic interventions to improve cardiovascular health and long-term cardiovascular outcomes in children with rheumatic disease are needed.

Full Text

Duke Authors

Cited Authors

  • Ardalan, K; Lloyd-Jones, DM; Schanberg, LE

Published Date

  • February 2022

Published In

Volume / Issue

  • 48 / 1

Start / End Page

  • 157 - 181

PubMed ID

  • 34798945

Electronic International Standard Serial Number (EISSN)

  • 1558-3163

Digital Object Identifier (DOI)

  • 10.1016/j.rdc.2021.09.006


  • eng

Conference Location

  • United States