Overview
Dr. Ardalan's clinical interests are in juvenile myositis, lupus, and scleroderma. He serves as Co-Director of the Duke Children's Myositis Center (Cure JM Foundation Center of Excellence) and as co-leader of the Duke Pediatric Lupus Clinic. Building on his prior expertise in psychometrics, outcomes research (including patient-reported outcome measures), and the impact of pediatric rheumatic diseases on mental health and cardiovascular disease risk, Dr. Ardalan led the Lupus Erythematosus and Dermatomyositis Stress and Cardiovascular Health (LEADS-CV) biopsychosocial cohort study evaluating associations of emotional distress, inflammation, and cardiovascular health in juvenile-onset lupus and dermatomyositis. Dr. Ardalan's current work is focused on the co-design and iterative refinement of behavioral interventions for youth with lupus and dermatomyositis as well as support for clinical trials in pediatric rheumatic diseases, including cellular therapies.
Current Duke Appointments & Affiliations
Assistant Professor of Pediatrics
·
2021 - Present
Pediatrics, Rheumatology,
Pediatrics
Recent News Items
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Recent Scholarly Works
Progression of skin-limited pediatric-onset discoid lupus erythematosus to diagnosis of systemic lupus erythematosus: Results of a multicenter, retrospective cohort study.
Journal article J Am Acad Dermatol · October 2026 BACKGROUND: Pediatric skin-limited discoid lupus erythematosus (DLE-only) is rare, with limited data on risk factors for progression to systemic lupus erythematosus (SLE). OBJECTIVE: To assess incidence, risk factors, and phenotype of pediatric DLE-only pr ... Full text Link to item CiteCongruence Between Child Self-Reported and Caregiver-Proxy-Reported Health-Related Quality of Life in Children With Juvenile Idiopathic Arthritis and Systemic Lupus Erythematosus.
Journal article J Rheumatol · May 1, 2026 OBJECTIVE: To explore congruence between child self-reported and caregiver-proxy-reported health-related quality of life (HRQOL) over time in juvenile idiopathic arthritis (JIA) and childhood-onset systemic lupus erythematosus (cSLE), and to identify facto ... Full text Link to item CiteSex Differences in PROMIS Pediatric Depressive Symptoms, Anxiety, and Psychological Stress Among Children and Adolescents Living With Pediatric Rheumatic Diseases.
Journal article J Rheumatol · May 1, 2026 OBJECTIVE: Children and adolescents living with juvenile idiopathic arthritis (JIA) and childhood-onset systemic lupus erythematosus (cSLE) frequently experience mental health comorbidities. This study evaluated sex differences in symptoms of depression, a ... Full text Link to item CiteRecent Grants
Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis Stress
ResearchPrincipal Investigator · Awarded by National Institute of Arthritis and Musculoskeletal and Skin Diseases · 2025 - 2030Lupus Erythematosus and Dermatomyositis Well-Being (LEAD-WELL): Mobile Health Intervention to Reduce Stress and Promote Cardiovascular Health Behaviors in Youth
ResearchPrincipal Investigator · Awarded by Rheumatology Research Foundation · 2026 - 2028A Phase 1/2, Open-Label Study to Evaluate the Safety and Efficacy of Autologous CD19-specific Chimeric Antigen Receptor T cells (CABA-201) in Subjects with Active Idiopathic Inflammatory Myopathy or A
Clinical TrialPrincipal Investigator · Awarded by Cabaletta Bio, Inc. · 2025 - 2028View All Grants
Education
University of Virginia, School of Medicine ·
2009
M.D.