Kaveh Ardalan | Scholars@Duke

Kaveh Ardalan
Assistant Professor of Pediatrics

Dr. Ardalan's clinical interests are in juvenile myositis, lupus, and scleroderma and he is co-director of the Duke-Cure JM Center of Excellence in Juvenile Idiopathic Inflammatory Myopathies. His research interests encompass health-related quality of life, patient-reported outcomes, mental health, psychological stress, adverse childhood experiences, cardiovascular health and outcomes research, psychometrics, and qualitative/mixed methods research.

Current Research Interests

Juvenile myositis, lupus, and localized scleroderma. Patient-reported outcomes, mental health, stress, adverse childhood experiences, cardiovascular health, psychometrics, and qualitative/mixed methods research.

Current Appointments & Affiliations

Assistant Professor of Pediatrics, Pediatrics, Rheumatology, Pediatrics 2021

Contact Information

kaveh.ardalan@duke.edu

Background
Education, Training, & Certifications
- Pediatric Rheumatology Fellowship, Pediatrics, Children's Hospital of Pittsburgh 2012 - 2015
- Residency, Pediatrics, New York University School of Medicine 2009 - 2012
- M.D., University of Virginia School of Medicine 2009
Medical Licensure
- 2019-01752 . North Carolina. 2019
- 036138461 . Illinois. 2015
Duke Appointment History
- Assistant Professor of Pediatrics, Pediatrics, Rheumatology, Pediatrics 2019 - 2020
Leadership & Clinical Positions at Duke
- Co-Director, Duke-Cure JM Center of Excellence in Juvenile Idiopathic Inflammatory Myopathies
Academic Positions Outside Duke
- Adjunct Assistant Professor of Pediatrics & Medical Social Sciences, Northwestern University Feinberg School of Medicine. 2019 - 2021
Recognition
In the News
- MAY 11, 2020
  
  NC Officials Monitoring COVID-19-Linked Illness that Strikes Childre
- MAY 8, 2020
  
  Duke University Doctors Keeping an Eye on Rare Pediatric Syndrome Possibly Linked to COVID-1
- JAN 31, 2020
  
  Localized Scleroderma Affects Quality of Life in Children, Study Find
- JUL 8, 2019
  
  Researchers pool experience to examine discoid lupus diagnosis, outcomes in childre
- DEC 10, 2018
  
  Hospitalizations longer, costlier for children with juvenile dermatomyositis
- OCT 20, 2018
  
  Kids with arthritis have higher prevalence of adverse childhood experiences
- OCT 24, 2017
  
  Dermatologists, rheumatologists differ in management of pediatric discoid lupus erythematosu
- SEP 21, 2017
  
  Length of stay, cost of care greater for non-White patients with dermatomyositi
Awards & Honors
Expertise
Subject Headings
Research
Selected Grants
- Psychological Stress and Cardiovascular Health in Juvenile Lupus and Dermatomyositis awarded by Rheumatology Research Foundation 2021 - 2024
- CARRA Early Investigator Chair Support awarded by Childhood Arthritis & Rheumatology Research Alliance, Inc. 2020 - 2023
- Facilitating international, multi-disciplinary collaboration in pediatric localized scleroderma research: International validation of outcome measures awarded by Childhood Arthritis & Rheumatology Research Alliance, Inc. 2021 - 2023
- Adverse Childhood Experiences in Juvenile Idiopathic Arthritis awarded by Albert Einstein College of Medicine 2019 - 2021
- CARRA Early Investigator Vice Chair Support awarded by Childhood Arthritis & Rheumatology Research Alliance, Inc. 2019 - 2021
- Pediatrics Juvenile Myositis program support awarded by Cure JM Foundation 2019 - 2021
- Vamorolone in Juvenile Autoimmune Myositis awarded by Cure JM Foundation 2020 - 2021
- Mental Health Screening in Juvenile Myositis: Pilot and Feasibility Study awarded by Childhood Arthritis & Rheumatology Research Alliance, Inc. 2019 - 2020
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Ochfeld, Elisa, Megan L. Curran, Sergio E. Chiarella, Kaveh Ardalan, and Amer Khojah. “A Case Report of SAVI Mimicking Early-Onset ANCA Vasculitis.” J Clin Immunol, June 5, 2021. https://doi.org/10.1007/s10875-021-01072-w.
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  - Saygin, Didem, Chester V. Oddis, Sedin Dzanko, Diane Koontz, Siamak Moghadam-Kia, Kaveh Ardalan, Theresa M. Coles, and Rohit Aggarwal. “Utility of patient-reported outcomes measurement information system (PROMIS) physical function form in inflammatory myopathy.” Semin Arthritis Rheum 51, no. 3 (April 15, 2021): 539–46. https://doi.org/10.1016/j.semarthrit.2021.03.018.
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  - Ardalan, Kaveh, Oluwatosin Adeyemi, Dawn M. Wahezi, Anne E. Caliendo, Megan L. Curran, Jessica Neely, Susan Kim, Colleen K. Correll, Emily J. Brunner, and Andrea M. Knight. “Parent Perspectives on Addressing Emotional Health for Children and Young Adults With Juvenile Myositis.” Arthritis Care Res (Hoboken) 73, no. 1 (January 2021): 18–29. https://doi.org/10.1002/acr.24466.
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  - Zigler, Christina K., Heidi Jacobe, Kaveh Ardalan, Theresa M. Coles, Suzane Lane, Kaila L. Schollaert, and Kathryn S. Torok. “The importance of development standards for anchoring vignettes: an illustrative example from pediatric localized scleroderma quality of life.” Qual Life Res 29, no. 12 (December 2020): 3263–72. https://doi.org/10.1007/s11136-020-02575-6.
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  - Zigler, C. K., K. Ardalan, A. Hernandez, A. E. Caliendo, K. E. Magee, M. A. Terry, C. M. Mann, and K. S. Torok. “Exploring the impact of paediatric localized scleroderma on health-related quality of life: focus groups with youth and caregivers.” Br J Dermatol 183, no. 4 (October 2020): 692–701. https://doi.org/10.1111/bjd.18879.
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  - Rubinstein, Tamar B., Danielle R. Bullock, Kaveh Ardalan, Wenzhu B. Mowrey, Nicole M. Brown, Laurie J. Bauman, and Ruth E. K. Stein. “Adverse Childhood Experiences Are Associated with Childhood-Onset Arthritis in a National Sample of US Youth: An Analysis of the 2016 National Survey of Children's Health.” J Pediatr, June 15, 2020. https://doi.org/10.1016/j.jpeds.2020.06.046.
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  - Zigler, C. K., K. Ardalan, S. Lane, K. L. Schollaert, and K. S. Torok. “A novel patient-reported outcome for paediatric localized scleroderma: a qualitative assessment of content validity.” Br J Dermatol 182, no. 3 (March 2020): 625–35. https://doi.org/10.1111/bjd.18512.
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  - Arkin, L. M., K. Buhr, H. Brandling-Bennett, Y. Chiu, B. Chong, M. Curran, R. Hunt, et al. “Practice-based differences in paediatric discoid lupus erythematosus.” Br J Dermatol 181, no. 4 (October 2019): 805–10. https://doi.org/10.1111/bjd.17780.
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  - Ardoin, Stacy P., R Paola Daly, Lyna Merzoug, Karin Tse, Kaveh Ardalan, Lisa Arkin, Andrea Knight, et al. “Research priorities in childhood-onset lupus: results of a multidisciplinary prioritization exercise.” Pediatr Rheumatol Online J 17, no. 1 (July 1, 2019): 32. https://doi.org/10.1186/s12969-019-0327-4.
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  - Kushner, C. J., M. Tarazi, R. G. Gaffney, R. Feng, K. Ardalan, H. A. Brandling-Bennett, L. Castelo-Soccio, et al. “Evaluation of the reliability and validity of the Cutaneous Lupus Erythematosus Disease Area and Severity Index (CLASI) in paediatric cutaneous lupus among paediatric dermatologists and rheumatologists.” Br J Dermatol 180, no. 1 (January 2019): 165–71. https://doi.org/10.1111/bjd.17012.
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  - Kwa, Michael C., Jonathan I. Silverberg, and Kaveh Ardalan. “Inpatient burden of juvenile dermatomyositis among children in the United States.” Pediatr Rheumatol Online J 16, no. 1 (November 13, 2018): 70. https://doi.org/10.1186/s12969-018-0286-1.
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  - Silverberg, Jonathan I., Lauren Kwa, Michael C. Kwa, Anne E. Laumann, and Kaveh Ardalan. “Cardiovascular and cerebrovascular comorbidities of juvenile dermatomyositis in US children: an analysis of the National Inpatient Sample.” Rheumatology (Oxford) 57, no. 4 (April 1, 2018): 694–702. https://doi.org/10.1093/rheumatology/kex465.
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  - Ardalan, K., G. E. Switzer, C. K. Zigler, N. M. Hershey, and K. S. Torok. “Psychometric properties of the children’s dermatology life quality index in pediatric localized scleroderma.” Journal of Scleroderma and Related Disorders 3, no. 2 (January 1, 2018): 175–81. https://doi.org/10.1177/2397198318760768.
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  - Thareja, Shalini, Kaitlyn Kollmann, Kaveh Ardalan, Marisa S. Klein-Gitelman, Amy S. Paller, and Lisa M. Arkin. “Oral Macrolides for the Dermatologic Manifestations of Blau Syndrome.” Jama Dermatol 153, no. 10 (October 1, 2017): 1066–67. https://doi.org/10.1001/jamadermatol.2017.2172.
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  - Ardalan, Kaveh, Christina K. Zigler, and Kathryn S. Torok. “Predictors of Longitudinal Quality of Life in Juvenile Localized Scleroderma.” Arthritis Care Res (Hoboken) 69, no. 7 (July 2017): 1082–87. https://doi.org/10.1002/acr.23101.
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  - Spencer, C. H., K. Rouster-Stevens, H. Gewanter, G. Syverson, R. Modica, K. Schmidt, H. Emery, et al. “Biologic therapies for refractory juvenile dermatomyositis: five years of experience of the Childhood Arthritis and Rheumatology Research Alliance in North America.” Pediatr Rheumatol Online J 15, no. 1 (June 13, 2017): 50. https://doi.org/10.1186/s12969-017-0174-0.
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  - Kwa, Michael C., Kaveh Ardalan, Anne E. Laumann, Beatrice Nardone, Dennis P. West, and Jonathan I. Silverberg. “Validation of International Classification of Diseases Codes for the Epidemiologic Study of Dermatomyositis.” Arthritis Care Res (Hoboken) 69, no. 5 (May 2017): 753–57. https://doi.org/10.1002/acr.23010.
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  - Rosenberg, Rebecca E., Kaveh Ardalan, Wai Wong, Sonya Patel, Gabrielle Gold-von Simson, David Feldman, Baron Lonner, et al. “Postoperative spinal fusion care in pediatric patients: Co-management decreases length of stay.” Bull Hosp Jt Dis (2013) 72, no. 3 (2014): 197–203.
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  - Ritterband, Lee M., Kaveh Ardalan, Frances P. Thorndike, Joshua C. Magee, Drew K. Saylor, Daniel J. Cox, James L. Sutphen, and Stephen M. Borowitz. “Real world use of an Internet intervention for pediatric encopresis.” J Med Internet Res 10, no. 2 (June 30, 2008): e16. https://doi.org/10.2196/jmir.1081.
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- Book Sections
  - Arkin, L. M., and K. Ardalan. “Morphea (Localized scleroderma).” In The 5-Minute Pediatric Consult, 8th Edition, 606–7, 2018.
- Conference Papers
  - Fawole, Oluwatunmise A., Michelle V. Reed, Julia G. Harris, Aimee Hersh, Martha Rodriguez, Karen Onel, Erica Lawson, et al. “Engaging patients and parents to improve mental health intervention for youth with rheumatological disease.” In Pediatr Rheumatol Online J, 19:19, 2021. https://doi.org/10.1186/s12969-021-00503-7.
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  - Danguecan, Ashley, Oluwatunmise Fawole, Michelle Reed, Julia Harris, Aimee Hersh, Martha Rodriguez, Karen Onel, et al. “Using a Patient-Engaged Approach to Identify Cross-Cutting Disease Factors Impacting Mental Health in Youth with Rheumatologic Disease.” In Arthritis & Rheumatology, Vol. 72, 2020.
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  - Patel, Ruchi, Valeria Esparza, Jin-Shei Lai, Elizabeth Gray, Rowland Chang, David Cella, and Kaveh Ardalan. “Comparison of PROMIS computerized adaptive testing-administered item banks versus fixed short forms in Juvenile Myositis.” In Quality of Life Research, 29:S22–S22, 2020.
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  - Wolfe, Madison, Amanda Robinson, Jin-Shei Lai, Theresa Coles, Elizabeth Gray, Rowland Chang, David Cella, and Kaveh Ardalan. “Estimation of Clinically Important Differences in Patient-Reported Outcomes Measurement Information System (PROMIS) Measures in Juvenile Myositis.” In Arthritis & Rheumatology, Vol. 72, 2020.
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  - Ardalan, Kaveh, Alison Manning, Brian Feldman, Gary Maslow, and Andrea Knight. “Feasibility and Pilot Study of Mental Health Screening in Juvenile Myositis.” In Arthritis & Rheumatology, 72:215–16, 2020.
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  - Danguecan, Ashley, Oluwatunmise Fawole, Michelle Reed, Julia Harris, Aimee Hersh, Martha Rodriquez, Karen Onel, et al. “Using a Patient-Engaged Approach to Identify Cross-Cutting Disease Factors Impacting Mental Health in Youth with Rheumatologic Disease.” In Arthritis & Rheumatology, 72:158–60, 2020.
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  - Ochfeld, Elisa, Megan Curran, Sergio Chiarella, Kaveh Ardalan, and Amer Khojah. “Recurrent Fever and Interstitial Lung Disease.” In Journal of Clinical Immunology, 40:S29–30, 2020.
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  - Ardalan, Kaveh, Oluwatosin Adeyemi, Dawn Wahezi, Anne Caliendo, Megan L. Curran, Jessica Neely, Susan Kim, Colleen Correll, Emily Brunner, and Andrea Knight. “Parent Perspectives on Addressing Emotional Health for Youth with Juvenile Myositis: A Qualitative Focus Group Study.” In Arthritis & Rheumatology, Vol. 71. WILEY, 2019.
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  - Ezeh, Nnenna, Kevin Buhr, Cordellia Nguyen, Ohoud Al Ahmed, Stacy Ardoin, Virginia Barton, Samantha Bell, et al. “Baseline Clinical and Serological Findings in Pediatric-Onset Discoid Lupus Erythematosus: Analysis of a Multicenter Retrospective Cohort Study.” In Arthritis & Rheumatology, Vol. 71. WILEY, 2019.
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  - Pachman, Lauren, Wil Marin, Gabrielle Morgan, Megan L. Curran, Kaveh Ardalan, Chiang-Ching Huang, and Eli Roberson. “Otoferlin Is Increased in Muscle and PBMCs from Untreated Children with Juvenile Dermatomyositis: Possible Association with Decreased Circulating Natural Killer Cells.” In Arthritis & Rheumatology, Vol. 71. WILEY, 2019.
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  - Patel, Ruchi, Valeria Esparza, Jin-Shei Lai, Elizabeth Gray, Rowland Chang, David Cella, and Kaveh Ardalan. “Comparison of PROMIS Computerized Adaptive Testing-Administered Item Banks versus Fixed Short Forms in Juvenile Myositis.” In Arthritis & Rheumatology, Vol. 71. WILEY, 2019.
    Link to Item
  - Ardalan, Kaveh, Elizabeth L. Gray, Julia Jungwha Lee, Madison L. Wolfe, Gabrielle A. Morgan, and Lauren M. Pachman. “Physical Function Trajectories in Children with Juvenile Myositis.” In Arthritis & Rheumatology, Vol. 70. WILEY, 2018.
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  - Arkin, Lisa, Kevin A. Buhr, Cordellia Nguyen, Heather Brandling-Bennett, Leslie Castelo-Soccio, Yvonne Chiu, Benjamin F. Chong, et al. “Baseline Features and Outcomes of Pediatric-Onset Discoid Lupus Erythematosus: Interim Data Analysis of a Multicenter Retrospective Cohort Study.” In Arthritis & Rheumatology, Vol. 70. WILEY, 2018.
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  - Fahey, Kyle J., Elizabeth L. Gray, Rowland W. Chang, David Cella, Lauren M. Pachman, and Kaveh Ardalan. “The Relationship of Pain, Fatigue and Emotional Distress with Quality of Life in Juvenile Myositis.” In Arthritis & Rheumatology, Vol. 70. WILEY, 2018.
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  - Rubinstein, Tamar, Danielle R. Bullock, Kaveh Ardalan, Wenzhu B. Mowrey, Nicole Brown, and Ruth E. K. Stein. “Increased Adverse Childhood Experiences in Children with Arthritis: An Analysis of the National Survey of Children's Health.” In Arthritis & Rheumatology, Vol. 70. WILEY, 2018.
    Link to Item
  - Ardalan, Kaveh, David Cella, Lauren M. Pachman, Elizabeth L. Gray, Julia Jungwha Lee, Kyle Fahey, Madison Wolfe, Megan L. Curran, Mariana C. Marques, and Rowland W. Chang. “Initial Validation of Patient-Reported Outcomes Measurement Information System (PROMIS (R)) in Children with Juvenile Myositis.” In Arthritis & Rheumatology, Vol. 69. WILEY, 2017.
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  - Ardalan, Kaveh, Hannah L. Palac, Julia Jungwha Lee, Madison Wolfe, Gabrielle A. Morgan, and Lauren M. Pachman. “Longitudinal Predictors of Physical Function in Juvenile Myositis.” In Arthritis & Rheumatology, Vol. 69. WILEY, 2017.
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  - Silverberg, Jonathan I., Lauren Kwa, Michael C. Kwa, Anne Laumann, and Kaveh Ardalan. “Cardiovascular and Cerebrovascular Comorbidities of Juvenile Dermatomyositis in United States Children.” In Arthritis & Rheumatology, Vol. 69. WILEY, 2017.
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  - Zigler, Christina K., Kaveh Ardalan, Kaila Schollaert-Fitch, Heidi Jacobe, and Kathryn S. Torok. “The Localized Scleroderma Quality of Life Instrument (LoSQI): Initial Validation in Pediatric Localized Scleroderma.” In Arthritis & Rheumatology, Vol. 69. WILEY, 2017.
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  - Kwa, Michael C., Kaveh Ardalan, Anne E. Laumann, and Jonathan I. Silverberg. “Predictors of Hospitalization, Length of Stay, and Cost of Care Among Adults With Dermatomyositis in the United States.” In Arthritis Care Res (Hoboken), 69:1391–99, 2017. https://doi.org/10.1002/acr.23190.
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  - Kwa, M., K. Ardalan, A. E. Laumann, and J. Silverberg. “176 Inpatient burden of dermatomyositis in united states adults.” In Journal of Investigative Dermatology, 137:S30–S30. Elsevier BV, 2017. https://doi.org/10.1016/j.jid.2017.02.191.
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  - Arkin, Lisa, Kaveh Ardalan, Heather Brandling-Bennett, Yvonne Chiu, Benjamin Chong, Megan Curran, Raegan Hunt, et al. “Practice-Based Differences Between Pediatric Rheumatologists and Dermatologists Caring for Children with Discoid Lupus.” In Arthritis & Rheumatology, Vol. 68. WILEY, 2016.
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  - Zigler, Christina K., Kaveh Ardalan, and Kathryn S. Torok. “Establishing Quality of Life Content Domains in Pediatric Localized Scleroderma.” In Arthritis & Rheumatology, Vol. 68. WILEY, 2016.
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  - Ardalan, Kaveh, Christina Kelsey, and Kathryn S. Torok. “Prospective, Standardized, Longitudinal Assessment Reveals Higher Prevalence of Extracutaneous Manifestations in a Pediatric Localized Scleroderma Cohort.” In Arthritis & Rheumatology, Vol. 67. WILEY-BLACKWELL, 2015.
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  - Ardalan, Kaveh, Christina Kelsey, and Kathryn S. Torok. “Predictors of Longitudinal Quality of Life Impact in Pediatric Localized Scleroderma.” In Arthritis & Rheumatology, Vol. 67. WILEY-BLACKWELL, 2015.
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  - Ardalan, Kaveh, Nicole Hershey, Jonathan Yabes, Eveline Wu, Suzanne C. Li, Robert C. Fuhlbrigge, C Egla Rabinovich, and Kathryn S. Torok. “Gender Differences in Pediatric Localized Scleroderma: Clinical and Patient-Reported Outcomes.” In Arthritis & Rheumatology, Vol. 67. WILEY-BLACKWELL, 2015.
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  - Ardalan, Kaveh, Nicole Hershey, Jonathan Yabes, and Kathryn S. Torok. “Relationship of Race, Ethnicity, and Outcomes in Pediatric Localized Scleroderma: Possible Differences in Disease Activity.” In Arthritis & Rheumatology, Vol. 67. WILEY-BLACKWELL, 2015.
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  - Ardalan, Kaveh, Christina Kelsey, and Kathryn S. Torok. “Relationships Between Physician and Patient Scored Clinical Outcome Measures In Pediatric Localized Scleroderma.” In Arthritis and Rheumatism, 65:S928–S928. WILEY-BLACKWELL, 2013.
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Teaching & Mentoring
Advising & Mentoring
- Current Mentees:
  Fellows, Doctoral, Postdocatoral:
  -Amanda Robinson, MD (Ann & Robert H. Lurie Children's Hospital of Chicago; Children's Hospital of Pittsburgh)
  -Nayimisha Balmuri, MD (Hospital for Special Surgery)
  
  Residents:
  -Jacqueline Fabricius, MD (Duke University Medical Center)
  
  Medical Students and Undergraduates:
  -Naira Ikram (Duke University - undergraduate)
  -Valeria Esparza, BS (University of Illinois-Chicago College of Medicine)
  -Ruchi Patel, BS (Northwestern University Feinberg School of Medicine)
  -Madison Wolfe, BA (Creighton University School of Medicine)
Teaching Activities
- Fellow Didactic Lectures; Duke Children's Community Symposium Presenter (CME course) 2020
Scholarly, Clinical, & Service Activities
Presentations & Appearances
- Management of Cutaneous Lupus. Pediatric Rheumatology Symposium (PRSYM) 2020 Meeting. May 2020 2020
- Outcomes in Pediatric Rheumatic Diseases: Interplay of Mental Health, Physical Health, and Quality of Life. CHDI Seminar Series. Children's Health & Discovery Initiative, Duke University. March 17, 2020 2020
Service to the Profession
Service to Duke
- Search Committee (Pediatric Rheumatology Division Head). June 2020 2020
Clinical Activities
- Co-Director of Duke-Cure JM Center of Excellence in Juvenile Idiopathic Inflammatory Myopathies (1.5 days/month of myositis clinic at Lenox-Baker).
  
  Additional clinical activities include: 2-3 days/month at Children's Health Center and 2 days/month at Brier Creek for general rheumatology clinic. Ad hoc coverage of lupus clinic (rheumatology/nephrology combined clinic), joint injection service, fellows continuity clinics. 6-8 weeks of inpatient pediatric rheumatology consult service per year.

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Education, Training, & Certifications

Medical Licensure

Duke Appointment History

Leadership & Clinical Positions at Duke

Academic Positions Outside Duke

In the News

Awards & Honors

Subject Headings

Selected Grants

Selected Publications

Academic Articles

Book Sections

Conference Papers

Advising & Mentoring

Teaching Activities

Presentations & Appearances

Service to the Profession

Service to Duke

Clinical Activities