MITI minimum information guidelines for highly multiplexed tissue images.

Journal Article (Journal Article)

The imminent release of tissue atlases combining multi-channel microscopy with single cell sequencing and other omics data from normal and diseased specimens creates an urgent need for data and metadata standards that guide data deposition, curation and release. We describe a Minimum Information about highly multiplexed Tissue Imaging (MITI) standard that applies best practices developed for genomics and other microscopy data to highly multiplexed tissue images and traditional histology.

Full Text

Duke Authors

Cited Authors

  • Schapiro, D; Yapp, C; Sokolov, A; Reynolds, SM; Chen, Y-A; Sudar, D; Xie, Y; Muhlich, J; Arias-Camison, R; Arena, S; Taylor, AJ; Nikolov, M; Tyler, M; Lin, J-R; Burlingame, EA; Human Tumor Atlas Network, ; Chang, YH; Farhi, SL; Thorsson, V; Venkatamohan, N; Drewes, JL; Pe'er, D; Gutman, DA; Herrmann, MD; Gehlenborg, N; Bankhead, P; Roland, JT; Herndon, JM; Snyder, MP; Angelo, M; Nolan, G; Swedlow, JR; Schultz, N; Merrick, DT; Mazzili, SA; Cerami, E; Rodig, SJ; Santagata, S; Sorger, PK

Published Date

  • March 2022

Published In

Volume / Issue

  • 19 / 3

Start / End Page

  • 262 - 267

PubMed ID

  • 35277708

Pubmed Central ID

  • PMC9009186

Electronic International Standard Serial Number (EISSN)

  • 1548-7105

Digital Object Identifier (DOI)

  • 10.1038/s41592-022-01415-4


  • eng

Conference Location

  • United States