Intrinsic and extrinsic regulators of Aux/IAA protein degradation dynamics.
Publication
, Journal Article
Figueiredo, MRAD; Strader, LC
Published in: Trends in biochemical sciences
October 2022
The plant hormone auxin acts through regulated degradation of Auxin/INDOLE-3-ACETIC ACID (Aux/IAA) proteins to regulate transcriptional events. In this review, we examine the composition and function of each Aux/IAA structural motif. We then focus on recent characterization of Aux/IAA N-terminal disordered regions, formation of secondary structure within these disordered regions, and post-translational modifications (PTMs) that affect Aux/IAA function and stability. We propose how structural variations between Aux/IAA family members may be tuned for differential transcriptional repression and degradation dynamics.
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Published In
Trends in biochemical sciences
DOI
ISSN
0968-0004
Publication Date
October 2022
Volume
47
Issue
10
Start / End Page
865 / 874
Related Subject Headings
- Proteolysis
- Plant Growth Regulators
- Nuclear Proteins
- Indoleacetic Acids
- Developmental Biology
- Arabidopsis Proteins
- 3404 Medicinal and biomolecular chemistry
- 3205 Medical biochemistry and metabolomics
- 3101 Biochemistry and cell biology
- 11 Medical and Health Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Figueiredo, M. R. A. D., & Strader, L. C. (2022). Intrinsic and extrinsic regulators of Aux/IAA protein degradation dynamics. Trends in Biochemical Sciences, 47(10), 865–874. https://doi.org/10.1016/j.tibs.2022.06.004
Figueiredo, Marcelo Rodrigues Alves de, and Lucia C. Strader. “Intrinsic and extrinsic regulators of Aux/IAA protein degradation dynamics.” Trends in Biochemical Sciences 47, no. 10 (October 2022): 865–74. https://doi.org/10.1016/j.tibs.2022.06.004.
Figueiredo MRAD, Strader LC. Intrinsic and extrinsic regulators of Aux/IAA protein degradation dynamics. Trends in biochemical sciences. 2022 Oct;47(10):865–74.
Figueiredo, Marcelo Rodrigues Alves de, and Lucia C. Strader. “Intrinsic and extrinsic regulators of Aux/IAA protein degradation dynamics.” Trends in Biochemical Sciences, vol. 47, no. 10, Oct. 2022, pp. 865–74. Epmc, doi:10.1016/j.tibs.2022.06.004.
Figueiredo MRAD, Strader LC. Intrinsic and extrinsic regulators of Aux/IAA protein degradation dynamics. Trends in biochemical sciences. 2022 Oct;47(10):865–874.
Published In
Trends in biochemical sciences
DOI
ISSN
0968-0004
Publication Date
October 2022
Volume
47
Issue
10
Start / End Page
865 / 874
Related Subject Headings
- Proteolysis
- Plant Growth Regulators
- Nuclear Proteins
- Indoleacetic Acids
- Developmental Biology
- Arabidopsis Proteins
- 3404 Medicinal and biomolecular chemistry
- 3205 Medical biochemistry and metabolomics
- 3101 Biochemistry and cell biology
- 11 Medical and Health Sciences