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Operationalizing Precision Cardiovascular Medicine: Three Innovations.

Publication ,  Journal Article
Wang, JJ; Aboulhosn, JA; Hofer, IS; Mahajan, A; Wang, Y; Vondriska, TM
Published in: Circ Res
October 14, 2016

For precision medicine to become a reality, we propose three changes. First, healthcare deliverables must be prioritized, enabling translation of knowledge to the clinic. Second, physicians and patients must be convinced to participate, requiring additional infrastructure in health systems. Third, discovery science must evolve to shift the preclinical landscape for innovation. We propose a change in the fundamental relationship between basic and clinical science: rather than two distinct entities between which concepts must be translated, we envision a natural hybrid of these approaches, wherein discovery science and clinical trials coincide in the same health systems and patient populations.

Duke Scholars

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Published In

Circ Res

DOI

EISSN

1524-4571

Publication Date

October 14, 2016

Volume

119

Issue

9

Start / End Page

984 / 987

Location

United States

Related Subject Headings

  • Therapies, Investigational
  • Precision Medicine
  • Patient Participation
  • Humans
  • Genomics
  • Delivery of Health Care
  • Clinical Trials as Topic
  • Cardiovascular System & Hematology
  • Cardiovascular Diseases
  • 3202 Clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
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Wang, J. J., Aboulhosn, J. A., Hofer, I. S., Mahajan, A., Wang, Y., & Vondriska, T. M. (2016). Operationalizing Precision Cardiovascular Medicine: Three Innovations. Circ Res, 119(9), 984–987. https://doi.org/10.1161/CIRCRESAHA.116.309776
Wang, Jessica J., Jamil A. Aboulhosn, Ira S. Hofer, Aman Mahajan, Yibin Wang, and Thomas M. Vondriska. “Operationalizing Precision Cardiovascular Medicine: Three Innovations.Circ Res 119, no. 9 (October 14, 2016): 984–87. https://doi.org/10.1161/CIRCRESAHA.116.309776.
Wang JJ, Aboulhosn JA, Hofer IS, Mahajan A, Wang Y, Vondriska TM. Operationalizing Precision Cardiovascular Medicine: Three Innovations. Circ Res. 2016 Oct 14;119(9):984–7.
Wang, Jessica J., et al. “Operationalizing Precision Cardiovascular Medicine: Three Innovations.Circ Res, vol. 119, no. 9, Oct. 2016, pp. 984–87. Pubmed, doi:10.1161/CIRCRESAHA.116.309776.
Wang JJ, Aboulhosn JA, Hofer IS, Mahajan A, Wang Y, Vondriska TM. Operationalizing Precision Cardiovascular Medicine: Three Innovations. Circ Res. 2016 Oct 14;119(9):984–987.

Published In

Circ Res

DOI

EISSN

1524-4571

Publication Date

October 14, 2016

Volume

119

Issue

9

Start / End Page

984 / 987

Location

United States

Related Subject Headings

  • Therapies, Investigational
  • Precision Medicine
  • Patient Participation
  • Humans
  • Genomics
  • Delivery of Health Care
  • Clinical Trials as Topic
  • Cardiovascular System & Hematology
  • Cardiovascular Diseases
  • 3202 Clinical sciences