Current Appointments & Affiliations
Professor in Medicine
·
2023 - Present
Medicine, Cardiology,
Medicine
Recent Publications
Dynamic molecular atlas of cardiac fibrosis at single-cell resolution shows CD248 in cardiac fibroblasts orchestrates interactions with immune cells.
Journal Article Nat Cardiovasc Res · April 2025 Post-injury remodeling is a complex process involving temporal specific cellular interactions in the injured tissue where the resident fibroblasts play multiple roles. Here, we performed single-cell and spatial transcriptome analysis in human and mouse inf ... Full text Link to item CiteBranched-chain amino acids promote hepatic Cyp7a1 expression and bile acid synthesis via suppressing FGF21-ERK pathway.
Journal Article Acta Pharmacol Sin · March 2025 Branched-chain amino acids (BCAAs) including leucine, isoleucine and valine have been linked with metabolic and cardiovascular diseases. BCAAs homeostasis is tightly controlled by their catabolic pathway. BCKA dehydrogenase (BCKD) complex is the rate-limit ... Full text Link to item CiteHordeum I genome unlocks adaptive evolution and genetic potential for crop improvement.
Journal Article Nat Plants · March 2025 Crop wild relatives (CWRs) are invaluable for crop improvement. Among these, Hordeum I-genome species exhibit exceptional tolerance to alkali and salt stresses. Here we present a chromosome-scale genome assembly of Hordeum brevisubulatum (II, 2n = 2x =14) ... Full text Link to item CiteEducation, Training & Certifications
Baylor, College of Medicine ·
1993
Ph.D.