Dawn of the Epi-LncRNAs: new path from Myheart.

Journal Article (Journal Article)

Myheart is a cardiac specific long-noncoding (lnc) RNA with targeted modulation of chromatin modifying SWI/SNF complex via direct interaction with Brg1. Genetic induction of Myheart in mouse heart has a significant protective effect against the pathogenesis of heart failure. LncRNAs are emerging epigenetic regulators with potentially important roles in cardiac development and diseases.

Full Text

Duke Authors

Cited Authors

  • Wang, Z; Wang, Y

Published Date

  • January 16, 2015

Published In

Volume / Issue

  • 116 / 2

Start / End Page

  • 235 - 236

PubMed ID

  • 25593274

Pubmed Central ID

  • PMC4313530

Electronic International Standard Serial Number (EISSN)

  • 1524-4571

Digital Object Identifier (DOI)

  • 10.1161/CIRCRESAHA.114.305490

Language

  • eng

Conference Location

  • United States