Sports-related brain injuries: connecting pathology to diagnosis.

Journal Article (Journal Article;Review)

Brain injuries are becoming increasingly common in athletes and represent an important diagnostic challenge. Early detection and management of brain injuries in sports are of utmost importance in preventing chronic neurological and psychiatric decline. These types of injuries incurred during sports are referred to as mild traumatic brain injuries, which represent a heterogeneous spectrum of disease. The most dramatic manifestation of chronic mild traumatic brain injuries is termed chronic traumatic encephalopathy, which is associated with profound neuropsychiatric deficits. Because chronic traumatic encephalopathy can only be diagnosed by postmortem examination, new diagnostic methodologies are needed for early detection and amelioration of disease burden. This review examines the pathology driving changes in athletes participating in high-impact sports and how this understanding can lead to innovations in neuroimaging and biomarker discovery.

Full Text

Duke Authors

Cited Authors

  • Pan, J; Connolly, ID; Dangelmajer, S; Kintzing, J; Ho, AL; Grant, G

Published Date

  • April 2016

Published In

Volume / Issue

  • 40 / 4

Start / End Page

  • E14 -

PubMed ID

  • 27032917

Electronic International Standard Serial Number (EISSN)

  • 1092-0684

Digital Object Identifier (DOI)

  • 10.3171/2016.1.FOCUS15607


  • eng

Conference Location

  • United States