Racial disparities in inpatient clinical presentation, treatment, and outcomes in brain metastasis.

Journal Article (Journal Article)

BACKGROUND: Few studies have assessed the impact of race on short-term patient outcomes in the brain metastasis population. The goal of this study is to evaluate the association of race with inpatient clinical presentation, treatment, in-hospital complications, and in-hospital mortality rates for patients with brain metastases (BM). METHOD: Using data collected from the National Inpatient Sample between 2004 and 2014, we retrospectively identified adult patients with a primary diagnosis of BM. Outcomes included nonroutine discharge, prolonged length of stay (pLOS), in-hospital complications, and mortality. RESULTS: Minority (Black, Hispanic/other) patients were less likely to receive surgical intervention compared to White patients (odds ratio [OR] 0.70; 95% confidence interval [CI] 0.66-0.74, p < 0.001; OR 0.88; 95% CI 0.84-0.93, p < 0.001). Black patients were more likely to develop an in-hospital complication than White patients (OR 1.35, 95% CI 1.28-1.41, p < 0.001). Additionally, minority patients were more likely to experience pLOS than White patients (OR 1.48; 95% CI 1.41-1.57, p < 0.001; OR 1.34; 95% CI 1.27-1.42, p < 0.001). Black patients were more likely to experience a nonroutine discharge (OR 1.25; 95% CI 1.19-1.31, p < 0.001) and higher in-hospital mortality than White (OR 1.13; 95% CI 1.03-1.23, p = 0.008). CONCLUSION: Our analysis demonstrated that race is associated with disparate short-term outcomes in patients with BM. More efforts are needed to address these disparities, provide equitable care, and allow for similar outcomes regardless of care.

Full Text

Duke Authors

Cited Authors

  • McCray, E; Waguia, R; de la Garza Ramos, R; Price, MJ; Williamson, T; Dalton, T; Sciubba, DM; Yassari, R; Goodwin, AN; Fecci, P; Johnson, MO; Chaichana, K; Goodwin, CR

Published Date

  • February 2023

Published In

Volume / Issue

  • 10 / 1

Start / End Page

  • 62 - 70

PubMed ID

  • 36659969

Pubmed Central ID

  • PMC9837769

International Standard Serial Number (ISSN)

  • 2054-2577

Digital Object Identifier (DOI)

  • 10.1093/nop/npac061


  • eng

Conference Location

  • England