Overview
I am a neuro-oncologist, neurologist, and palliative care physician at the Preston Robert Tisch Brain Tumor Center. I also provide neuro-oncology expertise for the National Tele-Oncology Program and National Precision Oncology Program at the Veteran's Health Administration. My clinical and research interests encompass supportive care and palliative care with a special interest in older adults with brain tumors. The incidence of malignant brain tumors like glioblastoma and non-malignant tumors like meningioma affect aging populations and it is crucial to be able to provide better care for these patients.
Current Appointments & Affiliations
Associate Professor of Neurosurgery
·
2025 - Present
Neurosurgery,
Neurosurgery
Associate Professor in Neurology
·
2025 - Present
Neurology, General & Community Neurology,
Neurology
Member of the Duke Cancer Institute
·
2018 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
A surgical window of opportunity trial evaluating the effect of the PCSK9 inhibitor evolocumab on tumoral MHC-I expression and CD8+ infiltration in glioma.
Journal Article Sci Rep · October 23, 2025 Many cancers evade immunosurveillance by downregulating surface major histocompatibility class (MHC)-I. Proprotein convertase subtilisin/kexin type 9 (PCSK9) promotes MHC-I degradation and is elevated in glioma. Evolocumab is a clinically approved PCSK9 in ... Full text Link to item CiteComparing Knowledge and Perceptions of Palliative Care Among Neuro-Oncology Patients, Caregivers, and Providers to a Representative U.S. Sample
Conference American Journal of Hospice and Palliative Medicine · September 1, 2025 Background: Primary brain tumors (PBTs) pose a significant health challenge, affecting patients and their caregivers. While early integration of palliative care (PC) has shown benefits in advanced cancer, its integration for PBT patients, particularly glio ... Full text CiteComparing Knowledge and Perceptions of Palliative Care Among Neuro-Oncology Patients, Caregivers, and Providers to a Representative U.S. Sample.
Journal Article Am J Hosp Palliat Care · September 2025 BackgroundPrimary brain tumors (PBTs) pose a significant health challenge, affecting patients and their caregivers. While early integration of palliative care (PC) has shown benefits in advanced cancer, its integration for PBT patients, particularly gliobl ... Full text Link to item CiteRecent Grants
ONC201 for the Treatment of Newly Diagnosed H3 K27M-mutant Diffuse Glioma Following Completion of Radiotherapy: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study
Clinical TrialPrincipal Investigator · Awarded by Chimerix, Inc. · 2023 - 2028Phase 2/3, Randomized, Multicenter Study to Evaluate the Efficacy and Safety of REC-2282 in Participants with NF2 Mutated Meningiomas
Clinical TrialPrincipal Investigator · Awarded by Recursion Pharmaceuticals, Inc · 2022 - 2027A Randomized Phase II Study of Nivolumab and Temozolomide vs Temozolomide alone in newly diagnosed elderly patients with Glioblastoma (NUTMEG)
Clinical TrialPrincipal Investigator · Awarded by University of Sydney · 2020 - 2022View All Grants
Education, Training & Certifications
Tulane University, School of Medicine ·
2011
M.D.
The George Washington University ·
2006
M.P.H.
Northwestern University ·
2001
B.A.