Role of vascular leukocytes in ovarian cancer neovascularization.
Publication
, Chapter
Balint, K; Conejo-Garcia, JR; Buckanovich, R; Coukos, G
2008
Vascular leukocytes are a unique population of CD45+ VE-cadherin+ cells with diverse functions. VLCs are capable of antigen presentation, as well as formation of endothelial-like structures in vitro and in vivo. VLCs are largely present among CD45+ cells infiltrating human ovarian carcinomas and are highly represented in the beta-defensin-VEGF-ID8 syngenic mouse model. Vascular leukocytes are a new and promising novel therapeutic target for anti-angiogenic therapy. Their unique mechanism merits thorough and extensive exploration in the future.
Duke Scholars
DOI
Publication Date
2008
Volume
622
Start / End Page
273 / 280
Related Subject Headings
- Ovarian Neoplasms
- Neovascularization, Pathologic
- Leukocytes
- Leukocyte Common Antigens
- Humans
- General & Internal Medicine
- Female
- Animals
- 32 Biomedical and clinical sciences
- 31 Biological sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Balint, K., Conejo-Garcia, J. R., Buckanovich, R., & Coukos, G. (2008). Role of vascular leukocytes in ovarian cancer neovascularization. (Vol. 622, pp. 273–280). https://doi.org/10.1007/978-0-387-68969-2_22
Balint, Klara, Jose R. Conejo-Garcia, Ron Buckanovich, and George Coukos. “Role of vascular leukocytes in ovarian cancer neovascularization.,” 622:273–80, 2008. https://doi.org/10.1007/978-0-387-68969-2_22.
Balint K, Conejo-Garcia JR, Buckanovich R, Coukos G. Role of vascular leukocytes in ovarian cancer neovascularization. In 2008. p. 273–80.
Balint, Klara, et al. Role of vascular leukocytes in ovarian cancer neovascularization. Vol. 622, 2008, pp. 273–80. Pubmed, doi:10.1007/978-0-387-68969-2_22.
Balint K, Conejo-Garcia JR, Buckanovich R, Coukos G. Role of vascular leukocytes in ovarian cancer neovascularization. 2008. p. 273–280.
DOI
Publication Date
2008
Volume
622
Start / End Page
273 / 280
Related Subject Headings
- Ovarian Neoplasms
- Neovascularization, Pathologic
- Leukocytes
- Leukocyte Common Antigens
- Humans
- General & Internal Medicine
- Female
- Animals
- 32 Biomedical and clinical sciences
- 31 Biological sciences