Carpal tunnel syndrome: updated evidence and new questions.

Journal Article (Journal Article;Review)

Carpal tunnel syndrome is the most common entrapment neuropathy, affecting quality of life for many people. Although it is a well recognised condition, new insights into epidemiology, diagnosis, and treatment have emerged in the past 6 years. The availability of disease-modifying treatments for rare systemic disorders associated with carpal tunnel syndrome (eg, amyloidosis) should alert clinicians to these diagnostic possibilities. Besides clinical evaluation and electrophysiology, the role of ultrasonography as a diagnostic tool has been confirmed and new ultrasound techniques have been applied, the clinical use and feasibility of which require further investigation. Surgical and non-surgical interventions are beneficial for the treatment of carpal tunnel syndrome and several treatment options are now available, giving clinicians the possibility to choose the best approach for every patient. New diagnostic and therapeutic techniques require further validation.

Full Text

Duke Authors

Cited Authors

  • Padua, L; Cuccagna, C; Giovannini, S; Coraci, D; Pelosi, L; Loreti, C; Bernabei, R; Hobson-Webb, LD

Published Date

  • March 2023

Published In

Volume / Issue

  • 22 / 3

Start / End Page

  • 255 - 267

PubMed ID

  • 36525982

Electronic International Standard Serial Number (EISSN)

  • 1474-4465

Digital Object Identifier (DOI)

  • 10.1016/S1474-4422(22)00432-X


  • eng

Conference Location

  • England