A method for the continuous calculation of the age of labeled red blood cells.
Publication
, Journal Article
Lindsell, CJ; Franco, RS; Smith, EP; Joiner, CH; Cohen, RM
Published in: Am J Hematol
June 2008
New methods for labeling red blood cells (RBC) and monitoring their survival have made it possible to explore changes in the properties of RBC as they age in the circulation. We have adapted a method, originally developed for studying wild animals, to calculate the age of a random sample of labeled RBC from their survival curve. We also show how this method can be expanded to allow continuous calculation of the mean age of the labeled RBC population at any time after labeling. It is expected that this analytical approach will be useful in the study of age-dependent RBC changes.
Duke Scholars
Published In
Am J Hematol
DOI
EISSN
1096-8652
Publication Date
June 2008
Volume
83
Issue
6
Start / End Page
454 / 457
Location
United States
Related Subject Headings
- Staining and Labeling
- Models, Theoretical
- Mice
- Methods
- Immunology
- Humans
- Erythrocytes
- Erythrocyte Aging
- Cytological Techniques
- Cell Survival
Citation
APA
Chicago
ICMJE
MLA
NLM
Lindsell, C. J., Franco, R. S., Smith, E. P., Joiner, C. H., & Cohen, R. M. (2008). A method for the continuous calculation of the age of labeled red blood cells. Am J Hematol, 83(6), 454–457. https://doi.org/10.1002/ajh.21148
Lindsell, Christopher J., Robert S. Franco, Eric P. Smith, Clinton H. Joiner, and Robert M. Cohen. “A method for the continuous calculation of the age of labeled red blood cells.” Am J Hematol 83, no. 6 (June 2008): 454–57. https://doi.org/10.1002/ajh.21148.
Lindsell CJ, Franco RS, Smith EP, Joiner CH, Cohen RM. A method for the continuous calculation of the age of labeled red blood cells. Am J Hematol. 2008 Jun;83(6):454–7.
Lindsell, Christopher J., et al. “A method for the continuous calculation of the age of labeled red blood cells.” Am J Hematol, vol. 83, no. 6, June 2008, pp. 454–57. Pubmed, doi:10.1002/ajh.21148.
Lindsell CJ, Franco RS, Smith EP, Joiner CH, Cohen RM. A method for the continuous calculation of the age of labeled red blood cells. Am J Hematol. 2008 Jun;83(6):454–457.
Published In
Am J Hematol
DOI
EISSN
1096-8652
Publication Date
June 2008
Volume
83
Issue
6
Start / End Page
454 / 457
Location
United States
Related Subject Headings
- Staining and Labeling
- Models, Theoretical
- Mice
- Methods
- Immunology
- Humans
- Erythrocytes
- Erythrocyte Aging
- Cytological Techniques
- Cell Survival