Brain spectrin, a membrane-associated protein related in structure and function to erythrocyte spectrin.

Journal Article (Journal Article)

An immunoreactive analogue of erythrocyte spectrin has been purified from brain membranes. This protein co-sediments with and cross-links actin filaments, associates with spectrin-binding sites on erythrocyte membranes, and has been visualized by rotary shadowing as an extended, flexible rod. The brain spectrin comprises 3% of the total membrane protein, and may have a major role in mediating linkage of actin to membranes.

Full Text

Duke Authors

Cited Authors

  • Bennett, V; Davis, J; Fowler, WE

Published Date

  • September 9, 1982

Published In

Volume / Issue

  • 299 / 5879

Start / End Page

  • 126 - 131

PubMed ID

  • 7110333

International Standard Serial Number (ISSN)

  • 0028-0836

Digital Object Identifier (DOI)

  • 10.1038/299126a0


  • eng

Conference Location

  • England