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Brain spectrin, a membrane-associated protein related in structure and function to erythrocyte spectrin.

Publication ,  Journal Article
Bennett, V; Davis, J; Fowler, WE
Published in: Nature
September 9, 1982

An immunoreactive analogue of erythrocyte spectrin has been purified from brain membranes. This protein co-sediments with and cross-links actin filaments, associates with spectrin-binding sites on erythrocyte membranes, and has been visualized by rotary shadowing as an extended, flexible rod. The brain spectrin comprises 3% of the total membrane protein, and may have a major role in mediating linkage of actin to membranes.

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Published In

Nature

DOI

ISSN

0028-0836

Publication Date

September 9, 1982

Volume

299

Issue

5879

Start / End Page

126 / 131

Location

England

Related Subject Headings

  • Swine
  • Spectrin
  • Protein Conformation
  • Peptides
  • Nerve Tissue Proteins
  • Membrane Proteins
  • Humans
  • General Science & Technology
  • Erythrocyte Membrane
  • Cell Membrane
 

Citation

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Bennett, V., Davis, J., & Fowler, W. E. (1982). Brain spectrin, a membrane-associated protein related in structure and function to erythrocyte spectrin. Nature, 299(5879), 126–131. https://doi.org/10.1038/299126a0
Bennett, V., J. Davis, and W. E. Fowler. “Brain spectrin, a membrane-associated protein related in structure and function to erythrocyte spectrin.Nature 299, no. 5879 (September 9, 1982): 126–31. https://doi.org/10.1038/299126a0.
Bennett V, Davis J, Fowler WE. Brain spectrin, a membrane-associated protein related in structure and function to erythrocyte spectrin. Nature. 1982 Sep 9;299(5879):126–31.
Bennett, V., et al. “Brain spectrin, a membrane-associated protein related in structure and function to erythrocyte spectrin.Nature, vol. 299, no. 5879, Sept. 1982, pp. 126–31. Pubmed, doi:10.1038/299126a0.
Bennett V, Davis J, Fowler WE. Brain spectrin, a membrane-associated protein related in structure and function to erythrocyte spectrin. Nature. 1982 Sep 9;299(5879):126–131.
Journal cover image

Published In

Nature

DOI

ISSN

0028-0836

Publication Date

September 9, 1982

Volume

299

Issue

5879

Start / End Page

126 / 131

Location

England

Related Subject Headings

  • Swine
  • Spectrin
  • Protein Conformation
  • Peptides
  • Nerve Tissue Proteins
  • Membrane Proteins
  • Humans
  • General Science & Technology
  • Erythrocyte Membrane
  • Cell Membrane