MR-compatible ventilator for small animals: computer-controlled ventilation for proton and noble gas imaging.

Journal Article (Journal Article)

We describe an MR-compatible ventilator that is computer controlled to generate a variety of breathing patterns, to minimize image degrading effects of breathing motion, and to support delivery of gas anesthesia and experimental inhalational gases. A key feature of this ventilator is the breathing valve that attaches directly to the endotracheal tube to reduce dead volume and allows independent control of inspiratory and expiratory phases of ventilation. This ventilator has been used in a wide variety of MR and x-ray microscopy studies of small animals, especially for MR imaging the lungs with hyperpolarized gases ((3)He & (129)Xe).

Full Text

Duke Authors

Cited Authors

  • Hedlund, LW; Cofer, GP; Owen, SJ; Allan Johnson, G

Published Date

  • July 2000

Published In

Volume / Issue

  • 18 / 6

Start / End Page

  • 753 - 759

PubMed ID

  • 10930785

International Standard Serial Number (ISSN)

  • 0730-725X

Digital Object Identifier (DOI)

  • 10.1016/s0730-725x(00)00154-5


  • eng

Conference Location

  • Netherlands