Cerebral cortical microfluorometry at isosbestic wavelengths for correction of vascular artifact.

Journal Article (Journal Article)

Microfluorometric measurements of cerebral cortical mitochondrial respiration in vivo are obscured by hemodynamic and oximetric artifacts. Isosbestic fluorometry provides appropriate correction for these vascular phenomena and permits simultaneous evaluation of mitochondrial nicotinamide adenine dinucleotide redox state, microcirculatory volume, and hemoglobin oxygenation.

Full Text

Duke Authors

Cited Authors

  • Kramer, RS; Pearlstein, RD

Published Date

  • August 17, 1979

Published In

Volume / Issue

  • 205 / 4407

Start / End Page

  • 693 - 696

PubMed ID

  • 223243

International Standard Serial Number (ISSN)

  • 0036-8075

Digital Object Identifier (DOI)

  • 10.1126/science.223243


  • eng

Conference Location

  • United States