Role of Ca++/calmodulin binding proteins in Aspergillus nidulans cell cycle regulation.

Journal Article (Journal Article;Review)

The goal of this review is to summarise the current knowledge concerning the targets of Ca++/calmodulin that are essential for cell cycle progression in lower eukaryotes. Emphasis is placed on Aspergillus nidulans since this is the only organism to date shown to posses essential Ca++ dependent calmodulin activated enzymes. Two such enzymes are the calmodulin activated protein phosphatase, calcineurin and the calmodulin dependent protein kinase. These proteins, each the product of a unique gene, are required for progression of quiescent spores into the proliferative cycle and also for execution of the nuclear division cycle in exponentially growing germlings.

Full Text

Duke Authors

Cited Authors

  • Nanthakumar, NN; Dayton, JS; Means, AR

Published Date

  • 1996

Published In

Volume / Issue

  • 2 /

Start / End Page

  • 217 - 228

PubMed ID

  • 9552398

International Standard Serial Number (ISSN)

  • 1087-2957

Digital Object Identifier (DOI)

  • 10.1007/978-1-4615-5873-6_21


  • eng

Conference Location

  • France