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T cell immunity in neonates.

Publication ,  Journal Article
Garcia, AM; Fadel, SA; Cao, S; Sarzotti, M
Published in: Immunol Res
2000

Typically, neonates exhibit decreased or aberrant cellular immune responses when compared to adults, resulting in increased susceptibility to infection. However, it is clear that newborns are able to generate adult-like protective T cell responses under certain conditions. The focus of our research is to understand the deficiencies within the neonatal immune system that lead to improper cellular responses and how priming conditions can be altered to elicit the appropriate T cell response necessary to protect against development of pathogen-induced disease. With these goals in mind, we are exploring the attributes of neonatal T cells and their development, as well as the conditions during priming that influence the resulting response to immune challenge during the neonatal period.

Duke Scholars

Published In

Immunol Res

DOI

ISSN

0257-277X

Publication Date

2000

Volume

22

Issue

2-3

Start / End Page

177 / 190

Location

United States

Related Subject Headings

  • T-Lymphocytes
  • Infant, Newborn
  • Immunology
  • Immunity, Cellular
  • Humans
  • Cell Differentiation
  • Animals, Newborn
  • Animals
  • Age Factors
  • 3204 Immunology
 

Citation

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Chicago
ICMJE
MLA
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Garcia, A. M., Fadel, S. A., Cao, S., & Sarzotti, M. (2000). T cell immunity in neonates. Immunol Res, 22(2–3), 177–190. https://doi.org/10.1385/IR:22:2-3:177
Garcia, A. M., S. A. Fadel, S. Cao, and M. Sarzotti. “T cell immunity in neonates.Immunol Res 22, no. 2–3 (2000): 177–90. https://doi.org/10.1385/IR:22:2-3:177.
Garcia AM, Fadel SA, Cao S, Sarzotti M. T cell immunity in neonates. Immunol Res. 2000;22(2–3):177–90.
Garcia, A. M., et al. “T cell immunity in neonates.Immunol Res, vol. 22, no. 2–3, 2000, pp. 177–90. Pubmed, doi:10.1385/IR:22:2-3:177.
Garcia AM, Fadel SA, Cao S, Sarzotti M. T cell immunity in neonates. Immunol Res. 2000;22(2–3):177–190.
Journal cover image

Published In

Immunol Res

DOI

ISSN

0257-277X

Publication Date

2000

Volume

22

Issue

2-3

Start / End Page

177 / 190

Location

United States

Related Subject Headings

  • T-Lymphocytes
  • Infant, Newborn
  • Immunology
  • Immunity, Cellular
  • Humans
  • Cell Differentiation
  • Animals, Newborn
  • Animals
  • Age Factors
  • 3204 Immunology