A physical map of the human genome.
Journal Article (Journal Article)
The human genome is by far the largest genome to be sequenced, and its size and complexity present many challenges for sequence assembly. The International Human Genome Sequencing Consortium constructed a map of the whole genome to enable the selection of clones for sequencing and for the accurate assembly of the genome sequence. Here we report the construction of the whole-genome bacterial artificial chromosome (BAC) map and its integration with previous landmark maps and information from mapping efforts focused on specific chromosomal regions. We also describe the integration of sequence data with the map.
Full Text
Duke Authors
Cited Authors
- McPherson, JD; Marra, M; Hillier, L; Waterston, RH; Chinwalla, A; Wallis, J; Sekhon, M; Wylie, K; Mardis, ER; Wilson, RK; Fulton, R; Kucaba, TA; Wagner-McPherson, C; Barbazuk, WB; Gregory, SG; Humphray, SJ; French, L; Evans, RS; Bethel, G; Whittaker, A; Holden, JL; McCann, OT; Dunham, A; Soderlund, C; Scott, CE; Bentley, DR; Schuler, G; Chen, HC; Jang, W; Green, ED; Idol, JR; Maduro, VV; Montgomery, KT; Lee, E; Miller, A; Emerling, S; Kucherlapati, ; Gibbs, R; Scherer, S; Gorrell, JH; Sodergren, E; Clerc-Blankenburg, K; Tabor, P; Naylor, S; Garcia, D; de Jong, PJ; Catanese, JJ; Nowak, N; Osoegawa, K; Qin, S; Rowen, L; Madan, A; Dors, M; Hood, L; Trask, B; Friedman, C; Massa, H; Cheung, VG; Kirsch, IR; Reid, T; Yonescu, R; Weissenbach, J; Bruls, T; Heilig, R; Branscomb, E; Olsen, A; Doggett, N; Cheng, JF; Hawkins, T; Myers, RM; Shang, J; Ramirez, L; Schmutz, J; Velasquez, O; Dixon, K; Stone, NE; Cox, DR; Haussler, D; Kent, WJ; Furey, T; Rogic, S; Kennedy, S; Jones, S; Rosenthal, A; Wen, G; Schilhabel, M; Gloeckner, G; Nyakatura, G; Siebert, R; Schlegelberger, B; Korenberg, J; Chen, XN; Fujiyama, A; Hattori, M; Toyoda, A; Yada, T; Park, HS; Sakaki, Y; Shimizu, N; Asakawa, S; Kawasaki, K; Sasaki, T; Shintani, A; Shimizu, A; Shibuya, K; Kudoh, J; Minoshima, S; Ramser, J; Seranski, P; Hoff, C; Poustka, A; Reinhardt, R; Lehrach, H; International Human Genome Mapping Consortium,
Published Date
- February 15, 2001
Published In
Volume / Issue
- 409 / 6822
Start / End Page
- 934 - 941
PubMed ID
- 11237014
International Standard Serial Number (ISSN)
- 0028-0836
Digital Object Identifier (DOI)
- 10.1038/35057157
Language
- eng
Conference Location
- England