The physical maps for sequencing human chromosomes 1, 6, 9, 10, 13, 20 and X.
Publication
, Journal Article
Bentley, DR; Deloukas, P; Dunham, A; French, L; Gregory, SG; Humphray, SJ; Mungall, AJ; Ross, MT; Carter, NP; Dunham, I; Scott, CE; Aubin, K ...
Published in: Nature
February 15, 2001
We constructed maps for eight chromosomes (1, 6, 9, 10, 13, 20, X and (previously) 22), representing one-third of the genome, by building landmark maps, isolating bacterial clones and assembling contigs. By this approach, we could establish the long-range organization of the maps early in the project, and all contig extension, gap closure and problem-solving was simplified by containment within local regions. The maps currently represent more than 94% of the euchromatic (gene-containing) regions of these chromosomes in 176 contigs, and contain 96% of the chromosome-specific markers in the human gene map. By measuring the remaining gaps, we can assess chromosome length and coverage in sequenced clones.
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Published In
Nature
DOI
ISSN
0028-0836
Publication Date
February 15, 2001
Volume
409
Issue
6822
Start / End Page
942 / 943
Location
England
Related Subject Headings
- X Chromosome
- Humans
- Genome, Human
- General Science & Technology
- Contig Mapping
- Chromosomes, Human, Pair 6
- Chromosomes, Human, Pair 20
- Chromosomes, Human, Pair 13
- Chromosomes, Human, Pair 10
- Chromosomes, Human, Pair 1
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Bentley, D. R., Deloukas, P., Dunham, A., French, L., Gregory, S. G., Humphray, S. J., … Wright, C. L. (2001). The physical maps for sequencing human chromosomes 1, 6, 9, 10, 13, 20 and X. Nature, 409(6822), 942–943. https://doi.org/10.1038/35057165
Bentley, D. R., P. Deloukas, A. Dunham, L. French, S. G. Gregory, S. J. Humphray, A. J. Mungall, et al. “The physical maps for sequencing human chromosomes 1, 6, 9, 10, 13, 20 and X.” Nature 409, no. 6822 (February 15, 2001): 942–43. https://doi.org/10.1038/35057165.
Bentley DR, Deloukas P, Dunham A, French L, Gregory SG, Humphray SJ, et al. The physical maps for sequencing human chromosomes 1, 6, 9, 10, 13, 20 and X. Nature. 2001 Feb 15;409(6822):942–3.
Bentley, D. R., et al. “The physical maps for sequencing human chromosomes 1, 6, 9, 10, 13, 20 and X.” Nature, vol. 409, no. 6822, Feb. 2001, pp. 942–43. Pubmed, doi:10.1038/35057165.
Bentley DR, Deloukas P, Dunham A, French L, Gregory SG, Humphray SJ, Mungall AJ, Ross MT, Carter NP, Dunham I, Scott CE, Ashcroft KJ, Atkinson AL, Aubin K, Beare DM, Bethel G, Brady N, Brook JC, Burford DC, Burrill WD, Burrows C, Butler AP, Carder C, Catanese JJ, Clee CM, Clegg SM, Cobley V, Coffey AJ, Cole CG, Collins JE, Conquer JS, Cooper RA, Culley KM, Dawson E, Dearden FL, Durbin RM, de Jong PJ, Dhami PD, Earthrowl ME, Edwards CA, Evans RS, Gillson CJ, Ghori J, Green L, Gwilliam R, Halls KS, Hammond S, Harper GL, Heathcott RW, Holden JL, Holloway E, Hopkins BL, Howard PJ, Howell GR, Huckle EJ, Hughes J, Hunt PJ, Hunt SE, Izmajlowicz M, Jones CA, Joseph SS, Laird G, Langford CF, Lehvaslaiho MH, Leversha MA, McCann OT, McDonald LM, McDowall J, Maslen GL, Mistry D, Moschonas NK, Neocleous V, Pearson DM, Phillips KJ, Porter KM, Prathalingam SR, Ramsey YH, Ranby SA, Rice CM, Rogers J, Rogers LJ, Sarafidou T, Scott DJ, Sharp GJ, Shaw-Smith CJ, Smink LJ, Soderlund C, Sotheran EC, Steingruber HE, Sulston JE, Taylor A, Taylor RG, Thorpe AA, Tinsley E, Warry GL, Whittaker A, Whittaker P, Williams SH, Wilmer TE, Wooster R, Wright CL. The physical maps for sequencing human chromosomes 1, 6, 9, 10, 13, 20 and X. Nature. 2001 Feb 15;409(6822):942–943.
Published In
Nature
DOI
ISSN
0028-0836
Publication Date
February 15, 2001
Volume
409
Issue
6822
Start / End Page
942 / 943
Location
England
Related Subject Headings
- X Chromosome
- Humans
- Genome, Human
- General Science & Technology
- Contig Mapping
- Chromosomes, Human, Pair 6
- Chromosomes, Human, Pair 20
- Chromosomes, Human, Pair 13
- Chromosomes, Human, Pair 10
- Chromosomes, Human, Pair 1