Initial sequencing and analysis of the human genome.

Published

Journal Article

The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and make freely available a draft sequence of the human genome. We also present an initial analysis of the data, describing some of the insights that can be gleaned from the sequence.

Full Text

Duke Authors

Cited Authors

  • Lander, ES; Linton, LM; Birren, B; Nusbaum, C; Zody, MC; Baldwin, J; Devon, K; Dewar, K; Doyle, M; FitzHugh, W; Funke, R; Gage, D; Harris, K; Heaford, A; Howland, J; Kann, L; Lehoczky, J; LeVine, R; McEwan, P; McKernan, K; Meldrim, J; Mesirov, JP; Miranda, C; Morris, W; Naylor, J; Raymond, C; Rosetti, M; Santos, R; Sheridan, A; Sougnez, C; Stange-Thomann, Y; Stojanovic, N; Subramanian, A; Wyman, D; Rogers, J; Sulston, J; Ainscough, R; Beck, S; Bentley, D; Burton, J; Clee, C; Carter, N; Coulson, A; Deadman, R; Deloukas, P; Dunham, A; Dunham, I; Durbin, R; French, L; Grafham, D; Gregory, S; Hubbard, T; Humphray, S; Hunt, A; Jones, M; Lloyd, C; McMurray, A; Matthews, L; Mercer, S; Milne, S; Mullikin, JC; Mungall, A; Plumb, R; Ross, M; Shownkeen, R; Sims, S; Waterston, RH; Wilson, RK; Hillier, LW; McPherson, JD; Marra, MA; Mardis, ER; Fulton, LA; Chinwalla, AT; Pepin, KH; Gish, WR; Chissoe, SL; Wendl, MC; Delehaunty, KD; Miner, TL; Delehaunty, A; Kramer, JB; Cook, LL; Fulton, RS; Johnson, DL; Minx, PJ; Clifton, SW; Hawkins, T; Branscomb, E; Predki, P; Richardson, P; Wenning, S; Slezak, T; Doggett, N; Cheng, JF; Olsen, A; Lucas, S; Elkin, C; Uberbacher, E; Frazier, M; Gibbs, RA; Muzny, DM; Scherer, SE; Bouck, JB; Sodergren, EJ; Worley, KC; Rives, CM; Gorrell, JH; Metzker, ML; Naylor, SL; Kucherlapati, RS; Nelson, DL; Weinstock, GM; Sakaki, Y; Fujiyama, A; Hattori, M; Yada, T; Toyoda, A; Itoh, T; Kawagoe, C; Watanabe, H; Totoki, Y; Taylor, T; Weissenbach, J; Heilig, R; Saurin, W; Artiguenave, F; Brottier, P; Bruls, T; Pelletier, E; Robert, C; Wincker, P; Smith, DR; Doucette-Stamm, L; Rubenfield, M; Weinstock, K; Lee, HM; Dubois, J; Rosenthal, A; Platzer, M; Nyakatura, G; Taudien, S; Rump, A; Yang, H; Yu, J; Wang, J; Huang, G; Gu, J; Hood, L; Rowen, L; Madan, A; Qin, S; Davis, RW; Federspiel, NA; Abola, AP; Proctor, MJ; Myers, RM; Schmutz, J; Dickson, M; Grimwood, J; Cox, DR; Olson, MV; Kaul, R; Shimizu, N; Kawasaki, K; Minoshima, S; Evans, GA; Athanasiou, M; Schultz, R; Roe, BA; Chen, F; Pan, H; Ramser, J; Lehrach, H; Reinhardt, R; McCombie, WR; de la Bastide, M; Dedhia, N; Blöcker, H; Hornischer, K; Nordsiek, G; Agarwala, R; Aravind, L; Bailey, JA; Bateman, A; Batzoglou, S; Birney, E; Bork, P; Brown, DG; Burge, CB; Cerutti, L; Chen, HC; Church, D; Clamp, M; Copley, RR; Doerks, T; Eddy, SR; Eichler, EE; Furey, TS; Galagan, J; Gilbert, JG; Harmon, C; Hayashizaki, Y; Haussler, D; Hermjakob, H; Hokamp, K; Jang, W; Johnson, LS; Jones, TA; Kasif, S; Kaspryzk, A; Kennedy, S; Kent, WJ; Kitts, P; Koonin, EV; Korf, I; Kulp, D; Lancet, D; Lowe, TM; McLysaght, A; Mikkelsen, T; Moran, JV; Mulder, N; Pollara, VJ; Ponting, CP; Schuler, G; Schultz, J; Slater, G; Smit, AF; Stupka, E; Szustakowki, J; Thierry-Mieg, D; Thierry-Mieg, J; Wagner, L; Wallis, J; Wheeler, R; Williams, A; Wolf, YI; Wolfe, KH; Yang, SP; Yeh, RF; Collins, F; Guyer, MS; Peterson, J; Felsenfeld, A; Wetterstrand, KA; Patrinos, A; Morgan, MJ; de Jong, P; Catanese, JJ; Osoegawa, K; Shizuya, H; Choi, S; Chen, YJ; International Human Genome Sequencing Consortium,

Published Date

  • February 2001

Published In

Volume / Issue

  • 409 / 6822

Start / End Page

  • 860 - 921

PubMed ID

  • 11237011

Pubmed Central ID

  • 11237011

Electronic International Standard Serial Number (EISSN)

  • 1476-4687

International Standard Serial Number (ISSN)

  • 0028-0836

Digital Object Identifier (DOI)

  • 10.1038/35057062

Language

  • eng