Synaptic vesicle biogenesis, docking, and fusion: a molecular description.
Publication
, Journal Article
Calakos, N; Scheller, RH
Published in: Physiol Rev
January 1996
Secretion of neurotransmitter is the primary means of intercellular communication within the nervous system. This process is regulated by a highly orchestrated cycle of membrane trafficking within the presynaptic nerve terminal. Characterization of proteins localized to the synaptic vesicle and the subsequent studies of their properties have led to a model for the biochemical pathway that underlies vesicle docking, activation, and fusion. The proteins found to function in the synapse are related to those in yeast and other organisms, demonstrating that the mechanisms that mediate vesicle trafficking are conserved in all eukaryotic species.
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Published In
Physiol Rev
DOI
ISSN
0031-9333
Publication Date
January 1996
Volume
76
Issue
1
Start / End Page
1 / 29
Location
United States
Related Subject Headings
- Synaptic Vesicles
- Physiology
- Neurotransmitter Agents
- Nerve Tissue Proteins
- Humans
- Endocytosis
- Cytoskeleton
- Axonal Transport
- Animals
- 3208 Medical physiology
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MLA
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Calakos, N., & Scheller, R. H. (1996). Synaptic vesicle biogenesis, docking, and fusion: a molecular description. Physiol Rev, 76(1), 1–29. https://doi.org/10.1152/physrev.1996.76.1.1
Calakos, N., and R. H. Scheller. “Synaptic vesicle biogenesis, docking, and fusion: a molecular description.” Physiol Rev 76, no. 1 (January 1996): 1–29. https://doi.org/10.1152/physrev.1996.76.1.1.
Calakos N, Scheller RH. Synaptic vesicle biogenesis, docking, and fusion: a molecular description. Physiol Rev. 1996 Jan;76(1):1–29.
Calakos, N., and R. H. Scheller. “Synaptic vesicle biogenesis, docking, and fusion: a molecular description.” Physiol Rev, vol. 76, no. 1, Jan. 1996, pp. 1–29. Pubmed, doi:10.1152/physrev.1996.76.1.1.
Calakos N, Scheller RH. Synaptic vesicle biogenesis, docking, and fusion: a molecular description. Physiol Rev. 1996 Jan;76(1):1–29.
Published In
Physiol Rev
DOI
ISSN
0031-9333
Publication Date
January 1996
Volume
76
Issue
1
Start / End Page
1 / 29
Location
United States
Related Subject Headings
- Synaptic Vesicles
- Physiology
- Neurotransmitter Agents
- Nerve Tissue Proteins
- Humans
- Endocytosis
- Cytoskeleton
- Axonal Transport
- Animals
- 3208 Medical physiology