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Pharmacotherapy of postoperative nausea and vomiting.

Publication ,  Journal Article
Habib, AS; Gan, TJ
Published in: Expert Opin Pharmacother
April 2003

Postoperative nausea and vomiting (PONV) are two of the most common and unpleasant side effects following anaesthesia and surgery. Despite the development of new anti-emetics and a vast amount of published research, PONV continues to be a problem, especially in high-risk patients. Recent interest has focused on the use of a combination of agents, acting on different receptors and the adoption of a multimodal approach to tackle this problem. The search for the most cost-effective strategy has also been a major goal. This article will discuss the risk factors and physiology of PONV, currently available therapies, the use of a multimodal approach and the cost-effectiveness of PONV management. Finally, recommendations for the prophylaxis and treatment of PONV will be discussed.

Duke Scholars

Published In

Expert Opin Pharmacother

DOI

ISSN

1465-6566

Publication Date

April 2003

Volume

4

Issue

4

Start / End Page

457 / 473

Location

England

Related Subject Headings

  • Serotonin Receptor Agonists
  • Postoperative Nausea and Vomiting
  • Pharmacology & Pharmacy
  • Male
  • Humans
  • Female
  • Drug Therapy
  • Cost-Benefit Analysis
  • Antiemetics
  • 3214 Pharmacology and pharmaceutical sciences
 

Citation

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Habib, A. S., & Gan, T. J. (2003). Pharmacotherapy of postoperative nausea and vomiting. Expert Opin Pharmacother, 4(4), 457–473. https://doi.org/10.1517/14656566.4.4.457
Habib, Ashraf S., and Tong J. Gan. “Pharmacotherapy of postoperative nausea and vomiting.Expert Opin Pharmacother 4, no. 4 (April 2003): 457–73. https://doi.org/10.1517/14656566.4.4.457.
Habib AS, Gan TJ. Pharmacotherapy of postoperative nausea and vomiting. Expert Opin Pharmacother. 2003 Apr;4(4):457–73.
Habib, Ashraf S., and Tong J. Gan. “Pharmacotherapy of postoperative nausea and vomiting.Expert Opin Pharmacother, vol. 4, no. 4, Apr. 2003, pp. 457–73. Pubmed, doi:10.1517/14656566.4.4.457.
Habib AS, Gan TJ. Pharmacotherapy of postoperative nausea and vomiting. Expert Opin Pharmacother. 2003 Apr;4(4):457–473.

Published In

Expert Opin Pharmacother

DOI

ISSN

1465-6566

Publication Date

April 2003

Volume

4

Issue

4

Start / End Page

457 / 473

Location

England

Related Subject Headings

  • Serotonin Receptor Agonists
  • Postoperative Nausea and Vomiting
  • Pharmacology & Pharmacy
  • Male
  • Humans
  • Female
  • Drug Therapy
  • Cost-Benefit Analysis
  • Antiemetics
  • 3214 Pharmacology and pharmaceutical sciences