Pharmacotherapy of postoperative nausea and vomiting.
Postoperative nausea and vomiting (PONV) are two of the most common and unpleasant side effects following anaesthesia and surgery. Despite the development of new anti-emetics and a vast amount of published research, PONV continues to be a problem, especially in high-risk patients. Recent interest has focused on the use of a combination of agents, acting on different receptors and the adoption of a multimodal approach to tackle this problem. The search for the most cost-effective strategy has also been a major goal. This article will discuss the risk factors and physiology of PONV, currently available therapies, the use of a multimodal approach and the cost-effectiveness of PONV management. Finally, recommendations for the prophylaxis and treatment of PONV will be discussed.
Duke Scholars
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Related Subject Headings
- Serotonin Receptor Agonists
- Postoperative Nausea and Vomiting
- Pharmacology & Pharmacy
- Male
- Humans
- Female
- Drug Therapy
- Cost-Benefit Analysis
- Antiemetics
- 3214 Pharmacology and pharmaceutical sciences
Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Serotonin Receptor Agonists
- Postoperative Nausea and Vomiting
- Pharmacology & Pharmacy
- Male
- Humans
- Female
- Drug Therapy
- Cost-Benefit Analysis
- Antiemetics
- 3214 Pharmacology and pharmaceutical sciences