Pharmacotherapy of postoperative nausea and vomiting.


Journal Article (Review)

Postoperative nausea and vomiting (PONV) are two of the most common and unpleasant side effects following anaesthesia and surgery. Despite the development of new anti-emetics and a vast amount of published research, PONV continues to be a problem, especially in high-risk patients. Recent interest has focused on the use of a combination of agents, acting on different receptors and the adoption of a multimodal approach to tackle this problem. The search for the most cost-effective strategy has also been a major goal. This article will discuss the risk factors and physiology of PONV, currently available therapies, the use of a multimodal approach and the cost-effectiveness of PONV management. Finally, recommendations for the prophylaxis and treatment of PONV will be discussed.

Full Text

Duke Authors

Cited Authors

  • Habib, AS; Gan, TJ

Published Date

  • April 2003

Published In

Volume / Issue

  • 4 / 4

Start / End Page

  • 457 - 473

PubMed ID

  • 12667109

Pubmed Central ID

  • 12667109

International Standard Serial Number (ISSN)

  • 1465-6566

Digital Object Identifier (DOI)

  • 10.1517/14656566.4.4.457


  • eng

Conference Location

  • England