Pharmacotherapy of postoperative nausea and vomiting.

Journal Article (Journal Article;Review)

Postoperative nausea and vomiting (PONV) are two of the most common and unpleasant side effects following anaesthesia and surgery. Despite the development of new anti-emetics and a vast amount of published research, PONV continues to be a problem, especially in high-risk patients. Recent interest has focused on the use of a combination of agents, acting on different receptors and the adoption of a multimodal approach to tackle this problem. The search for the most cost-effective strategy has also been a major goal. This article will discuss the risk factors and physiology of PONV, currently available therapies, the use of a multimodal approach and the cost-effectiveness of PONV management. Finally, recommendations for the prophylaxis and treatment of PONV will be discussed.

Full Text

Duke Authors

Cited Authors

  • Habib, AS; Gan, TJ

Published Date

  • April 2003

Published In

Volume / Issue

  • 4 / 4

Start / End Page

  • 457 - 473

PubMed ID

  • 12667109

International Standard Serial Number (ISSN)

  • 1465-6566

Digital Object Identifier (DOI)

  • 10.1517/14656566.4.4.457


  • eng

Conference Location

  • England