Ultrastructural distribution of collagen types I-VI in aging human retinal vessels.

Journal Article (Journal Article)

Retinal vessels from freshly enucleated human eyes were classified into three stages of the hyalinisation process. The distribution of collagen types I-VI within the vessel walls was studied ultrastructurally by immunogold labelling combined with the tissue preparation techniques of cryoultramicrotomy and London resin white embedding. Collagen types I, III, IV, V, and VI were found in large vessels, types I, IV, and V plus small amounts of III and VI in small vessels, and types I, IV, and V in capillaries. Hyalinised vessel walls consisted mainly of types I, IV, and VI collagen.

Full Text

Duke Authors

Cited Authors

  • Marshall, GE; Konstas, AG; Lee, WR

Published Date

  • April 1990

Published In

Volume / Issue

  • 74 / 4

Start / End Page

  • 228 - 232

PubMed ID

  • 2337548

Pubmed Central ID

  • PMC1042067

International Standard Serial Number (ISSN)

  • 0007-1161

Digital Object Identifier (DOI)

  • 10.1136/bjo.74.4.228


  • eng

Conference Location

  • England