Incorporation of a Laguerre-Gauss channelized Hotelling observer for false-positive reduction in a mammographic mass CAD system.

Journal Article (Journal Article)

Previously, we developed a simple Laguerre-Gauss (LG) channelized Hotelling observer (CHO) for incorporation into our mass computer-aided detection (CAD) system. This LG-CHO was trained using initial detection suspicious region data and was empirically optimized for free parameters. For the study presented in this paper, we wish to create a more optimal mass detection observer based on a novel combination of LG channels. A large set of LG channels with differing free parameters was created. Each of these channels was applied to the suspicious regions, and an output test statistic was determined. A stepwise feature selection algorithm was used to determine which LG channels would combine best to detect masses. These channels were combined using a HO to create a single template for the mass CAD system. Results from free-response receiver operating characteristic curves demonstrated that the incorporation of the novel LG-CHO into the CAD system slightly improved performance in high-sensitivity regions.

Full Text

Duke Authors

Cited Authors

  • Baydush, AH; Catarious, DM; Lo, JY; Floyd, CE

Published Date

  • June 2007

Published In

Volume / Issue

  • 20 / 2

Start / End Page

  • 196 - 202

PubMed ID

  • 17505872

Pubmed Central ID

  • PMC3043903

International Standard Serial Number (ISSN)

  • 0897-1889

Digital Object Identifier (DOI)

  • 10.1007/s10278-007-9009-8


  • eng

Conference Location

  • United States