Chloroquine resistance of Plasmodium falciparum is associated with severity of disease in Nigerian children.
Publication
, Journal Article
Olumese, PE; Amodu, OK; Björkman, A; Adeyemo, AA; Gbadegesin, RA; Walker, O
Published in: Trans R Soc Trop Med Hyg
2002
Chloroquine resistance of Plasmodium falciparum in vitro was significantly higher in isolates from patients with severe malaria than those with uncomplicated disease. This association may be due to either progression of uncomplicated to severe disease following chloroquine failure or increased virulence of chloroquine-resistant parasites. The implication of this for antimalarial treatment policy is discussed.
Duke Scholars
Published In
Trans R Soc Trop Med Hyg
DOI
ISSN
0035-9203
Publication Date
2002
Volume
96
Issue
4
Start / End Page
418 / 420
Location
England
Related Subject Headings
- Tropical Medicine
- Regression Analysis
- Plasmodium falciparum
- Nigeria
- Male
- Infant
- Humans
- Female
- Drug Resistance
- Chloroquine
Citation
APA
Chicago
ICMJE
MLA
NLM
Olumese, P. E., Amodu, O. K., Björkman, A., Adeyemo, A. A., Gbadegesin, R. A., & Walker, O. (2002). Chloroquine resistance of Plasmodium falciparum is associated with severity of disease in Nigerian children. Trans R Soc Trop Med Hyg, 96(4), 418–420. https://doi.org/10.1016/s0035-9203(02)90378-0
Olumese, P. E., O. K. Amodu, A. Björkman, A. A. Adeyemo, R. A. Gbadegesin, and O. Walker. “Chloroquine resistance of Plasmodium falciparum is associated with severity of disease in Nigerian children.” Trans R Soc Trop Med Hyg 96, no. 4 (2002): 418–20. https://doi.org/10.1016/s0035-9203(02)90378-0.
Olumese PE, Amodu OK, Björkman A, Adeyemo AA, Gbadegesin RA, Walker O. Chloroquine resistance of Plasmodium falciparum is associated with severity of disease in Nigerian children. Trans R Soc Trop Med Hyg. 2002;96(4):418–20.
Olumese, P. E., et al. “Chloroquine resistance of Plasmodium falciparum is associated with severity of disease in Nigerian children.” Trans R Soc Trop Med Hyg, vol. 96, no. 4, 2002, pp. 418–20. Pubmed, doi:10.1016/s0035-9203(02)90378-0.
Olumese PE, Amodu OK, Björkman A, Adeyemo AA, Gbadegesin RA, Walker O. Chloroquine resistance of Plasmodium falciparum is associated with severity of disease in Nigerian children. Trans R Soc Trop Med Hyg. 2002;96(4):418–420.
Published In
Trans R Soc Trop Med Hyg
DOI
ISSN
0035-9203
Publication Date
2002
Volume
96
Issue
4
Start / End Page
418 / 420
Location
England
Related Subject Headings
- Tropical Medicine
- Regression Analysis
- Plasmodium falciparum
- Nigeria
- Male
- Infant
- Humans
- Female
- Drug Resistance
- Chloroquine