Chloroquine resistance of Plasmodium falciparum is associated with severity of disease in Nigerian children.

Journal Article (Journal Article)

Chloroquine resistance of Plasmodium falciparum in vitro was significantly higher in isolates from patients with severe malaria than those with uncomplicated disease. This association may be due to either progression of uncomplicated to severe disease following chloroquine failure or increased virulence of chloroquine-resistant parasites. The implication of this for antimalarial treatment policy is discussed.

Full Text

Duke Authors

Cited Authors

  • Olumese, PE; Amodu, OK; Björkman, A; Adeyemo, AA; Gbadegesin, RA; Walker, O

Published Date

  • 2002

Published In

Volume / Issue

  • 96 / 4

Start / End Page

  • 418 - 420

PubMed ID

  • 12497979

International Standard Serial Number (ISSN)

  • 0035-9203

Digital Object Identifier (DOI)

  • 10.1016/s0035-9203(02)90378-0


  • eng

Conference Location

  • England