Chloroquine resistance of Plasmodium falciparum is associated with severity of disease in Nigerian children.
Journal Article (Journal Article)
Chloroquine resistance of Plasmodium falciparum in vitro was significantly higher in isolates from patients with severe malaria than those with uncomplicated disease. This association may be due to either progression of uncomplicated to severe disease following chloroquine failure or increased virulence of chloroquine-resistant parasites. The implication of this for antimalarial treatment policy is discussed.
Full Text
Duke Authors
Cited Authors
- Olumese, PE; Amodu, OK; Björkman, A; Adeyemo, AA; Gbadegesin, RA; Walker, O
Published Date
- 2002
Published In
Volume / Issue
- 96 / 4
Start / End Page
- 418 - 420
PubMed ID
- 12497979
International Standard Serial Number (ISSN)
- 0035-9203
Digital Object Identifier (DOI)
- 10.1016/s0035-9203(02)90378-0
Language
- eng
Conference Location
- England