Overview
Molecular genetics of glomerular disease
Genetic risk factors for childhood onset idiopathic nephrotic syndrome
Genetic risk factors for childhood onset idiopathic nephrotic syndrome
Current Duke Appointments & Affiliations
Wilburt C. Davison Distinguished Professor
·
2021 - Present
Pediatrics, Nephrology,
Pediatrics
Professor of Pediatrics
·
2018 - Present
Pediatrics, Nephrology,
Pediatrics
Associate Dean for Physician-Scientist Development
·
2021 - Present
School of Medicine
Director of the Office of Physician-Science Development in the School of Medicine
·
2021 - Present
School of Medicine
Chief, Division of Pediatric Nephrology
·
2025 - Present
Pediatrics, Nephrology,
Pediatrics
Professor in Medicine
·
2018 - Present
Medicine, Nephrology,
Medicine
Affiliate of the Duke Molecular Physiology Institute
·
2014 - Present
Duke Molecular Physiology Institute,
Institutes and Centers
Recent Scholarly Works
Food Insecurity and Blood Pressure in West Africans with Chronic Kidney Disease
Journal article Clinical Epidemiology and Global Health · July 1, 2026 Background/aims: Food insecurity, limited/uncertain access to adequate food, is a growing concern, especially in low- and middle-income countries, where it may exacerbate chronic kidney disease (CKD). Evidence on the relationship between food insecurity an ... Full text CiteUpdate on APOL1 and chronic kidney diseases in children.
Journal article Pediatr Nephrol · June 5, 2026 Chronic kidney disease (CKD) is a major global health burden that disproportionately impacts people of recent African ancestry. The discovery of risk variants in the apolipoprotein L1 (APOL1) gene has transformed the understanding of racial disparities in ... Full text Link to item CitePolygenic risk scores and HLA class II variants are biomarkers of corticosteroid response in childhood nephrotic syndrome.
Journal article Kidney Int · June 2026 INTRODUCTION: Nephrotic syndrome (NS), a common glomerular disease in children, is classified based on response to corticosteroid therapy as either steroid-sensitive nephrotic syndrome (SSNS), or steroid-resistant nephrotic syndrome (SRNS). However, there ... Full text Link to item CiteRecent Grants
2/3 CTSA K12 Program at Duke University
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2025 - 2030APOL1 - associated nephropathy from human-derived, intrarenal perspective
ResearchPrincipal Investigator · Awarded by Boston Children's Hospital · 2025 - 2030Phase 2b Multicentre, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Dose-Ranging Study to Assess the Efficacy, Safety, and Tolerability of AZD2373 in Participants with APOL1-Mediated Ki
Clinical TrialPrincipal Investigator · Awarded by AstraZeneca AB · 2025 - 2029View All Grants
Education
University of Ibadan, College of Medicine (Nigeria) ·
1987
M.B.B.S.