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Benign pediatric localization-related epilepsies. Part I. Syndromes in infancy.

Publication ,  Journal Article
Chahine, LM; Mikati, MA
Published in: Epileptic Disord
September 2006

There is currently increasing interest in identifying and classifying pediatric benign epilepsy syndromes and recently several new syndromes have been recognized. Benign epilepsy syndromes, by definition, occur in children with normal developmental history, respond well to therapy, and remit without sequelae. The large majority of children with benign epilepsy syndromes follow a truly benign course. The concept of benign epilepsy syndromes has, however, been challenged by the minority of patients who continue to have seizures despite therapy, develop new seizures after initial remission, or exhibit neuropsychological abnormalities. Without long-term follow-up, benignity can not be truly ascertained a priori. Thus it may be preferable to use the terms possible and probable before the name of a specific syndrome until such time that the diagnosis of a definite benign syndrome is confirmed on long-term follow-up. In this review of the pediatric benign localization-related epilepsy syndromes, we address the concept of benignity and the process of diagnosis of a benign epilepsy syndrome. In addition we review the epidemiology, clinical manifestations, EEG findings, work-up, diagnostic criteria, differential diagnosis, genetics, management and prognosis of benign infantile familial convulsions, benign partial epilepsy in infancy with complex partial seizures, benign partial epilepsy in infancy with secondarily generalized seizures, benign infantile convulsions associated with mild gastroenteritis, and benign infantile focal epilepsy with midline spikes and waves during sleep.

Duke Scholars

Published In

Epileptic Disord

ISSN

1294-9361

Publication Date

September 2006

Volume

8

Issue

3

Start / End Page

169 / 183

Location

United States

Related Subject Headings

  • Neurology & Neurosurgery
  • Infant, Newborn
  • Infant
  • Humans
  • Epilepsy, Benign Neonatal
  • Electroencephalography
  • Diagnosis, Differential
  • Child, Preschool
  • 3209 Neurosciences
  • 3202 Clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Chahine, L. M., & Mikati, M. A. (2006). Benign pediatric localization-related epilepsies. Part I. Syndromes in infancy. Epileptic Disord, 8(3), 169–183.
Chahine, Lama M., and Mohamad A. Mikati. “Benign pediatric localization-related epilepsies. Part I. Syndromes in infancy.Epileptic Disord 8, no. 3 (September 2006): 169–83.
Chahine LM, Mikati MA. Benign pediatric localization-related epilepsies. Part I. Syndromes in infancy. Epileptic Disord. 2006 Sep;8(3):169–83.
Chahine, Lama M., and Mohamad A. Mikati. “Benign pediatric localization-related epilepsies. Part I. Syndromes in infancy.Epileptic Disord, vol. 8, no. 3, Sept. 2006, pp. 169–83.
Chahine LM, Mikati MA. Benign pediatric localization-related epilepsies. Part I. Syndromes in infancy. Epileptic Disord. 2006 Sep;8(3):169–183.

Published In

Epileptic Disord

ISSN

1294-9361

Publication Date

September 2006

Volume

8

Issue

3

Start / End Page

169 / 183

Location

United States

Related Subject Headings

  • Neurology & Neurosurgery
  • Infant, Newborn
  • Infant
  • Humans
  • Epilepsy, Benign Neonatal
  • Electroencephalography
  • Diagnosis, Differential
  • Child, Preschool
  • 3209 Neurosciences
  • 3202 Clinical sciences