Mistaking a house for a face: neural correlates of misperception in healthy humans.
Published
Journal Article
Individuals with normal vision can sometimes momentarily mistake one object for another. In this functional magnetic resonance imaging study, we investigated how extrastriate visual regions respond during these erroneous perceptual judgements. Subjects were asked to discriminate images of houses and faces that were degraded such that they were close to an individually defined threshold for perception. On correct trials, voxels localized on the inferior occipital (OFA), fusiform (FFA) and parahippocampal (PPA) gyri exhibited selectivity for face and house images as expected. On incorrect trials, no face- or place-selectivity was observed for OFA or PPA. However, consistent with 'predictive coding' accounts of perception, we observed that the FFA also responded robustly on trials where a house was misperceived as a face, and concurrent activation was observed in medio-frontal and right parietal regions previously implicated in decision making under uncertainty. We suggest that FFA responses during misperception may be driven by a predictive top-down signal from these regions.
Full Text
Duke Authors
Cited Authors
- Summerfield, C; Egner, T; Mangels, J; Hirsch, J
Published Date
- April 2006
Published In
Volume / Issue
- 16 / 4
Start / End Page
- 500 - 508
PubMed ID
- 16014866
Pubmed Central ID
- 16014866
Electronic International Standard Serial Number (EISSN)
- 1460-2199
International Standard Serial Number (ISSN)
- 1047-3211
Digital Object Identifier (DOI)
- 10.1093/cercor/bhi129
Language
- eng