In vivo He-3 MR images of guinea pig lungs.

Journal Article (Journal Article)

The authors imaged the lungs of live guinea pigs with hyperpolarized (HP) helium-3 as a magnetic resonance (MR) signal source. HP He-3 gas produced through spin exchange with rubidium metal vapor was delivered through an MR-compatible, small-animal ventilator. Two- and three-dimensional lung images acquired with ventilation-gated, radial k-space sampling showed complete ventilation of both lungs. All images were of high quality, demonstrating that HP He-3 allows high-signal-intensity MR imaging in living systems.

Full Text

Duke Authors

Cited Authors

  • Black, RD; Middleton, HL; Cates, GD; Cofer, GP; Driehuys, B; Happer, W; Hedlund, LW; Johnson, GA; Shattuck, MD; Swartz, JC

Published Date

  • June 1996

Published In

Volume / Issue

  • 199 / 3

Start / End Page

  • 867 - 870

PubMed ID

  • 8638019

International Standard Serial Number (ISSN)

  • 0033-8419

Digital Object Identifier (DOI)

  • 10.1148/radiology.199.3.8638019


  • eng

Conference Location

  • United States