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In vivo He-3 MR images of guinea pig lungs.

Publication ,  Journal Article
Black, RD; Middleton, HL; Cates, GD; Cofer, GP; Driehuys, B; Happer, W; Hedlund, LW; Johnson, GA; Shattuck, MD; Swartz, JC
Published in: Radiology
June 1996

The authors imaged the lungs of live guinea pigs with hyperpolarized (HP) helium-3 as a magnetic resonance (MR) signal source. HP He-3 gas produced through spin exchange with rubidium metal vapor was delivered through an MR-compatible, small-animal ventilator. Two- and three-dimensional lung images acquired with ventilation-gated, radial k-space sampling showed complete ventilation of both lungs. All images were of high quality, demonstrating that HP He-3 allows high-signal-intensity MR imaging in living systems.

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Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

June 1996

Volume

199

Issue

3

Start / End Page

867 / 870

Location

United States

Related Subject Headings

  • Radioisotopes
  • Nuclear Medicine & Medical Imaging
  • Male
  • Magnetic Resonance Imaging
  • Lung
  • Helium
  • Guinea Pigs
  • Animals
  • 3202 Clinical sciences
  • 11 Medical and Health Sciences
 

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Black, R. D., Middleton, H. L., Cates, G. D., Cofer, G. P., Driehuys, B., Happer, W., … Swartz, J. C. (1996). In vivo He-3 MR images of guinea pig lungs. Radiology, 199(3), 867–870. https://doi.org/10.1148/radiology.199.3.8638019
Black, R. D., H. L. Middleton, G. D. Cates, G. P. Cofer, B. Driehuys, W. Happer, L. W. Hedlund, G. A. Johnson, M. D. Shattuck, and J. C. Swartz. “In vivo He-3 MR images of guinea pig lungs.Radiology 199, no. 3 (June 1996): 867–70. https://doi.org/10.1148/radiology.199.3.8638019.
Black RD, Middleton HL, Cates GD, Cofer GP, Driehuys B, Happer W, et al. In vivo He-3 MR images of guinea pig lungs. Radiology. 1996 Jun;199(3):867–70.
Black, R. D., et al. “In vivo He-3 MR images of guinea pig lungs.Radiology, vol. 199, no. 3, June 1996, pp. 867–70. Pubmed, doi:10.1148/radiology.199.3.8638019.
Black RD, Middleton HL, Cates GD, Cofer GP, Driehuys B, Happer W, Hedlund LW, Johnson GA, Shattuck MD, Swartz JC. In vivo He-3 MR images of guinea pig lungs. Radiology. 1996 Jun;199(3):867–870.
Journal cover image

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

June 1996

Volume

199

Issue

3

Start / End Page

867 / 870

Location

United States

Related Subject Headings

  • Radioisotopes
  • Nuclear Medicine & Medical Imaging
  • Male
  • Magnetic Resonance Imaging
  • Lung
  • Helium
  • Guinea Pigs
  • Animals
  • 3202 Clinical sciences
  • 11 Medical and Health Sciences