Prevalence of clinical isolates of Cryptococcus gattii serotype C among patients with AIDS in Sub-Saharan Africa.
Journal Article (Journal Article)
Cryptococcus gattii is a group of exogenous, neurotropic yeasts that possess the capsular serotype B or C. Isolates of serotype C are extremely rare and, until recently, were known to infect only immunocompetent individuals. We genotyped 176 isolates of Cryptococcus from patients in sub-Saharan Africa who had AIDS; 22 (13.7%) of 161 isolates from Botswana and 2 (13.3%) of 15 isolates from Malawi were C. gattii serotype C strains. All of these serotype C strains belong to the rare VGIV genotype, possess the MAT alpha mating-type allele, and exhibit little genetic diversity.
Full Text
Duke Authors
Cited Authors
- Litvintseva, AP; Thakur, R; Reller, LB; Mitchell, TG
Published Date
- September 1, 2005
Published In
Volume / Issue
- 192 / 5
Start / End Page
- 888 - 892
PubMed ID
- 16088839
Pubmed Central ID
- 16088839
International Standard Serial Number (ISSN)
- 0022-1899
Digital Object Identifier (DOI)
- 10.1086/432486
Language
- eng
Conference Location
- United States