Candida glabrata endophthalmitis following penetrating keratoplasty.

Journal Article (Journal Article)

We report a case of Candida glabrata endophthalmitis following penetrating keratoplasty in a 57-year-old man. The infection was thought to be treated successfully with intravitreal amphotericin B but flared 7 months later following cataract extraction and eventually required explantation of the intraocular lens and therapeutic keratoplasty. The literature regarding this rare infection is reviewed. Candida glabrata, an uncommon ocular pathogen, is being reported with increasing frequency and with a notable predilection for post-keratoplasty eyes. In the 10 reported cases, there is 100% concordance between host and donor tissue cultures. In half the cases, there was a latent period of several months. These infections can be difficult to treat because C glabrata is often resistant to the antifungal agents commonly used to treat Candida albicans.

Full Text

Duke Authors

Cited Authors

  • Caldwell, MC; Perfect, JR; Carlson, AN; Proia, AD

Published Date

  • March 2009

Published In

Volume / Issue

  • 35 / 3

Start / End Page

  • 598 - 602

PubMed ID

  • 19251157

Electronic International Standard Serial Number (EISSN)

  • 1873-4502

Digital Object Identifier (DOI)

  • 10.1016/j.jcrs.2008.08.046


  • eng

Conference Location

  • United States