Network integration of the adrenergic system in cardiac hypertrophy.

Journal Article (Journal Article;Review)

Adrenergic receptors play a pivotal role in regulating cardiac function in response to a constantly changing environment. Altered alpha and beta adrenergic receptor signaling in vivo is associated with cardiac hypertrophy and failure. This review focuses on the different roles of adrenergic receptors in regulating cardiac function under normal and pathological conditions. Understanding the signaling mechanisms of these receptors in the context of the heart is likely to provide a better therapeutic approach towards treatment of heart failure.

Full Text

Duke Authors

Cited Authors

  • Barki-Harrington, L; Perrino, C; Rockman, HA

Published Date

  • August 15, 2004

Published In

Volume / Issue

  • 63 / 3

Start / End Page

  • 391 - 402

PubMed ID

  • 15276464

Pubmed Central ID

  • 15276464

International Standard Serial Number (ISSN)

  • 0008-6363

Digital Object Identifier (DOI)

  • 10.1016/j.cardiores.2004.03.011


  • eng

Conference Location

  • England