Parathyroid lesions: characterization with dual-phase arterial and venous enhanced CT of the neck.

Journal Article (Journal Article)

This clinical report describes the enhancement characteristics of hypersecreting parathyroid lesions on dual-phase neck CT. We retrospectively analyzed the enhancement characteristics of 5 pathologically confirmed PTH-secreting lesions on dual-phase CT examinations. Attenuation values were measured for PTH-secreting lesions, vascular structures (CCA and IJV), and soft tissue structures (thyroid gland, jugulodigastric lymph node, and submandibular gland). From the attenuation values, "relative enhancement washout percentage" and "tissue-vascular ratio" were calculated and compared. All lesions decreased in attenuation from arterial to venous phase, while the mean attenuation values of other soft tissue structures increased. A high relative enhancement washout percentage was correlated with parathyroid lesions (P < .006). The tissue-CCA ratio and tissue-IJV ratio for PTH-secreting lesions in the arterial phase were statistically significantly higher compared with soft tissue structures (P < .05). If these results are validated in future larger studies, noncontrast and delayed venous phases of 4D-CT could be eliminated to markedly reduce radiation exposure.

Full Text

Duke Authors

Cited Authors

  • Gafton, AR; Glastonbury, CM; Eastwood, JD; Hoang, JK

Published Date

  • May 2012

Published In

Volume / Issue

  • 33 / 5

Start / End Page

  • 949 - 952

PubMed ID

  • 22241395

Pubmed Central ID

  • PMC7968817

Electronic International Standard Serial Number (EISSN)

  • 1936-959X

Digital Object Identifier (DOI)

  • 10.3174/ajnr.A2885


  • eng

Conference Location

  • United States