Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Neuroradiology Fellowship, Emory University 1996 - 1998
  • M.D., State University of New York - Buffalo 1992
• 

  Previous Appointments & Affiliations

  • Associate Professor of Radiology, Radiology, Neuroradiology, Radiology 2005 - 2009
  • Assistant Professor of Radiology, Radiology, Neuroradiology, Radiology 1998 - 2005
  • Instructor, Temporary in the Department of Radiology, Radiology, Neuroradiology, Radiology 1998
• Publications & Artistic Works
• 

  Selected Publications

  • Books

    • Miles, K. A., J. D. Eastwood, and M. König. Multidetector computed tomography in cerebrovascular disease: CT perfusion imaging, 2007.
    • Miles, K. A., J. D. Eastwood, and M. König. Preface, 2007.

  • Academic Articles

    • Nguyen, Xuan V., Louise Davies, James D. Eastwood, and Jenny K. Hoang. “Extrapulmonary Findings and Malignancies in Participants Screened With Chest CT in the National Lung Screening Trial.” J Am Coll Radiol 14, no. 3 (March 2017): 324–30. https://doi.org/10.1016/j.jacr.2016.09.044.
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    • Galvin, Leo, Jorge D. Oldan, Manisha Bahl, James D. Eastwood, Julie A. Sosa, and Jenny K. Hoang. “Parathyroid 4D CT and Scintigraphy: What Factors Contribute to Missed Parathyroid Lesions?” Otolaryngol Head Neck Surg 154, no. 5 (May 2016): 847–53. https://doi.org/10.1177/0194599816630711.
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    • Bahl, Manisha, Julie A. Sosa, James D. Eastwood, Hasan A. Hobbs, Rendon C. Nelson, and Jenny K. Hoang. “Using the 3-tiered system for categorizing workup of incidental thyroid nodules detected on CT, MRI, or PET/CT: how many cancers would be missed?” Thyroid 24, no. 12 (December 2014): 1772–78. https://doi.org/10.1089/thy.2014.0066.
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    • Amrhein, T. J., B. E. Paxton, M. P. Lungren, N. T. Befera, H. R. Collins, C. Yurko, J. D. Eastwood, and R. K. Kilani. “Physician self-referral and imaging use appropriateness: negative cervical spine MRI frequency as an assessment metric.” Ajnr Am J Neuroradiol 35, no. 12 (December 2014): 2248–53. https://doi.org/10.3174/ajnr.A4076.
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    • Hoang, J. K., A. Riofrio, M. R. Bashir, P. G. Kranz, and J. D. Eastwood. “High variability in radiologists' reporting practices for incidental thyroid nodules detected on CT and MRI.” Ajnr Am J Neuroradiol 35, no. 6 (June 2014): 1190–94. https://doi.org/10.3174/ajnr.A3834.
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    • Hoang, J. K., K. R. Choudhury, J. D. Eastwood, R. M. Esclamado, G. H. Lyman, T. M. Shattuck, and X. V. Nguyen. “An exponential growth in incidence of thyroid cancer: trends and impact of CT imaging.” Ajnr Am J Neuroradiol 35, no. 4 (April 2014): 778–83. https://doi.org/10.3174/ajnr.A3743.
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    • Hobbs, Hasan A., Manisha Bahl, Rendon C. Nelson, James D. Eastwood, Ramon M. Esclamado, and Jenny K. Hoang. “Applying the Society of Radiologists in Ultrasound recommendations for fine-needle aspiration of thyroid nodules: effect on workup and malignancy detection.” Ajr Am J Roentgenol 202, no. 3 (March 2014): 602–7. https://doi.org/10.2214/AJR.13.11219.
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    • Holbrook, John F., James D. Eastwood, and Ramsey K. Kilani. “Intracranial abscess as a complication of allergic fungal sinusitis.” J Neuroimaging 24, no. 1 (2014): 95–98. https://doi.org/10.1111/j.1552-6569.2011.00670.x.
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    • Lungren, Matthew P., Timothy J. Amrhein, Ben E. Paxton, Ramesh C. Srinivasan, Heather R. Collins, James D. Eastwood, and Ramsey K. Kilani. “Physician self-referral: frequency of negative findings at MR imaging of the knee as a marker of appropriate utilization.” Radiology 269, no. 3 (December 2013): 810–15. https://doi.org/10.1148/radiol.13130281.
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    • Nguyen, X. V., K Roy Choudhury, J. D. Eastwood, G. H. Lyman, R. M. Esclamado, J. D. Werner, and J. K. Hoang. “Incidental thyroid nodules on CT: evaluation of 2 risk-categorization methods for work-up of nodules.” Ajnr Am J Neuroradiol 34, no. 9 (September 2013): 1812–17. https://doi.org/10.3174/ajnr.A3487.
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    • Amrhein, Timothy J., Matthew P. Lungren, Ben E. Paxton, Ramesh Srinivasan, Sin-Ho Jung, Miao Yu, James D. Eastwood, and Ramsey K. Kilani. “Journal Club: Shoulder MRI utilization: relationship of physician MRI equipment ownership to negative study frequency.” Ajr Am J Roentgenol 201, no. 3 (September 2013): 605–10. https://doi.org/10.2214/AJR.12.9977.
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    • Gafton, A. R., S. M. Cohen, J. D. Eastwood, M. K. Dang, and J. K. Hoang. “Recurrent laryngopyocele: CT-guided hookwire localization for re-excision surgery.” Ajnr Am J Neuroradiol 34, no. 4 (April 2013): E39–42. https://doi.org/10.3174/ajnr.A2810.
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    • Hoang, J. K., D. P. Massoglia, M. A. Apostol, C. D. Lascola, J. D. Eastwood, and P. G. Kranz. “CT-guided cervical transforaminal steroid injections: where should the needle tip be located?” Ajnr Am J Neuroradiol 34, no. 3 (March 2013): 688–92. https://doi.org/10.3174/ajnr.A3266.
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    • Schauberger, J. S., P. G. Kranz, K. R. Choudhury, J. D. Eastwood, L. Gray, and J. K. Hoang. “CT-guided lumbar nerve root injections: are we using the correct radiation dose settings?” Ajnr Am J Neuroradiol 33, no. 10 (November 2012): 1855–59. https://doi.org/10.3174/ajnr.A3096.
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    • Hoang, J. K., R. De Jesus, J. D. Eastwood, A. R. Gafton, and D. L. Witsell. “CT-guided hookwire placement: a technical innovation for preoperative localization of nonpalpable cervical lymph nodes.” Ajnr Am J Neuroradiol 33, no. 7 (August 2012): E104–6. https://doi.org/10.3174/ajnr.A2538.
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    • Paxton, Ben E., Matthew P. Lungren, Ramesh C. Srinivasan, Sin-Ho Jung, Miao Yu, James D. Eastwood, and Ramsey K. Kilani. “Physician self-referral of lumbar spine MRI with comparative analysis of negative study rates as a marker of utilization appropriateness.” Ajr Am J Roentgenol 198, no. 6 (June 2012): 1375–79. https://doi.org/10.2214/AJR.11.7730.
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    • Gafton, A. R., C. M. Glastonbury, J. D. Eastwood, and J. K. Hoang. “Parathyroid lesions: characterization with dual-phase arterial and venous enhanced CT of the neck.” Ajnr Am J Neuroradiol 33, no. 5 (May 2012): 949–52. https://doi.org/10.3174/ajnr.A2885.
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    • Hoang, Jenny K., Terry T. Yoshizumi, Kingshuk Roy Choudhury, Giao B. Nguyen, Greta Toncheva, Andreia R. Gafton, James D. Eastwood, Carolyn Lowry, and Lynne M. Hurwitz. “Organ-based dose current modulation and thyroid shields: techniques of radiation dose reduction for neck CT.” Ajr Am J Roentgenol 198, no. 5 (May 2012): 1132–38. https://doi.org/10.2214/AJR.11.7445.
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    • Hoang, Jenny K., Phillip Raduazo, David M. Yousem, and James D. Eastwood. “What to do with incidental thyroid nodules on imaging? An approach for the radiologist.” Semin Ultrasound Ct Mr 33, no. 2 (April 2012): 150–57. https://doi.org/10.1053/j.sult.2011.12.004.
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    • Hoang, Jenny K., Terry T. Yoshizumi, Giao Nguyen, Greta Toncheva, Kingshuk Roy Choudhury, Andreia R. Gafton, James D. Eastwood, Carolyn Lowry, and Lynne M. Hurwitz. “Variation in tube voltage for adult neck MDCT: effect on radiation dose and image quality.” Ajr Am J Roentgenol 198, no. 3 (March 2012): 621–27. https://doi.org/10.2214/AJR.11.6831.
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    • Hoang, Jenny K., Andreia R. Gafton, James D. Eastwood, Luke F. Chen, and Lynne M. Hurwitz. “Correlation of cross-sectional diameter with image quality and radiation exposure in MDCT examinations of the neck.” Ajr Am J Roentgenol 197, no. 5 (November 2011): W904–9. https://doi.org/10.2214/AJR.10.5476.
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    • Hoang, Jenny K., Terry T. Yoshizumi, Greta Toncheva, Linda Gray, Andreia R. Gafton, Billy K. Huh, James D. Eastwood, Christopher D. Lascola, and Lynne M. Hurwitz. “Radiation dose exposure for lumbar spine epidural steroid injections: a comparison of conventional fluoroscopy data and CT fluoroscopy techniques.” Ajr Am J Roentgenol 197, no. 4 (October 2011): 778–82. https://doi.org/10.2214/AJR.10.6102.
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    • Welling, R. D., J. A. Olson, P. G. Kranz, J. D. Eastwood, and J. K. Hoang. “Bilateral retropharyngeal parathyroid hyperplasia detected with 4D multidetector row CT.” Ajnr Am J Neuroradiol 32, no. 5 (May 2011): E80–82. https://doi.org/10.3174/ajnr.A2104.
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    • Hoang, Jenny K., Barton F. Branstetter, James D. Eastwood, and Christine M. Glastonbury. “Multiplanar CT and MRI of collections in the retropharyngeal space: is it an abscess?” Ajr Am J Roentgenol 196, no. 4 (April 2011): W426–32. https://doi.org/10.2214/AJR.10.5116.
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    • Hoang, Jenny K., Christine M. Glastonbury, Luke F. Chen, Jaime K. Salvatore, and James D. Eastwood. “CT mucosal window settings: a novel approach to evaluating early T-stage head and neck carcinoma.” Ajr Am J Roentgenol 195, no. 4 (October 2010): 1002–6. https://doi.org/10.2214/AJR.09.4149.
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    • Hoang, Jenny K., James D. Eastwood, Christopher L. Tebbit, and Christine M. Glastonbury. “Multiplanar sinus CT: a systematic approach to imaging before functional endoscopic sinus surgery.” Ajr Am J Roentgenol 194, no. 6 (June 2010): W527–36. https://doi.org/10.2214/AJR.09.3584.
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    • Hoang, J. K., J. D. Eastwood, and C. M. Glastonbury. “What's in a name? Eponyms in head and neck imaging.” Clin Radiol 65, no. 3 (March 2010): 237–45. https://doi.org/10.1016/j.crad.2009.10.008.
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    • Kranz, P. G., and J. D. Eastwood. “Does diffusion-weighted imaging represent the ischemic core? An evidence-based systematic review (American Journal of Neuroradiology 30, (1206-1212)).” American Journal of Neuroradiology 30, no. 7 (August 1, 2009). https://doi.org/10.3174/ajnr.A1779.
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    • Kranz, P. G., and J. D. Eastwood. “Does diffusion-weighted imaging represent the ischemic core? An evidence-based systematic review.” Ajnr Am J Neuroradiol 30, no. 6 (June 2009): 1206–12. https://doi.org/10.3174/ajnr.A1547.
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    • Wintermark, Max, Gregory W. Albers, Andrei V. Alexandrov, Jeffry R. Alger, Roland Bammer, Jean-Claude Baron, Stephen Davis, et al. “Acute stroke imaging research roadmap.” Ajnr Am J Neuroradiol 29, no. 5 (May 2008): e23–30. https://doi.org/10.1161/STROKEAHA.107.512319.
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    • Gururangan, Sridharan, Wendy Frankel, Russell Broaddus, Mark Clendenning, Leigha Senter, Marie McDonald, James Eastwood, et al. “Multifocal anaplastic astrocytoma in a patient with hereditary colorectal cancer, transcobalamin II deficiency, agenesis of the corpus callosum, mental retardation, and inherited PMS2 mutation.” Neuro Oncol 10, no. 1 (February 2008): 93–97. https://doi.org/10.1215/15228517-2007-037.
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    • Laslo, A. M., J. D. Eastwood, P. Pakkiri, F. Chen, and T. Y. Lee. “CT perfusion-derived mean transit time predicts early mortality and delayed vasospasm after experimental subarachnoid hemorrhage.” Ajnr Am J Neuroradiol 29, no. 1 (January 2008): 79–85. https://doi.org/10.3174/ajnr.A0747.
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    • Laslo, A. M., J. D. Eastwood, F. -. X. Chen, and T. -. Y. Lee. “Dynamic CT perfusion imaging in subarachnoid hemorrhage-related vasospasm.” Ajnr Am J Neuroradiol 27, no. 3 (March 2006): 624–31.
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    • Wintermark, M., M. Sesay, E. Barbier, K. Borbély, W. P. Dillon, J. D. Eastwood, T. C. Glenn, et al. “Comparative overview of brain perfusion imaging techniques.” J Neuroradiol 32, no. 5 (December 2005): 294–314. https://doi.org/10.1016/s0150-9861(05)83159-1.
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    • Greenwood, Robert S., Larry A. Tupler, J Kenneth Whitt, Anne Buu, Carrie B. Dombeck, Amanda G. Harp, Martha E. Payne, James D. Eastwood, K Ranga R. Krishnan, and James R. MacFall. “Brain morphometry, T2-weighted hyperintensities, and IQ in children with neurofibromatosis type 1.” Arch Neurol 62, no. 12 (December 2005): 1904–8. https://doi.org/10.1001/archneur.62.12.1904.
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    • Nguyen, T. B., C. Lum, J. D. Eastwood, P. K. Stys, M. Hogan, and M. Goyal. “Hyperperfusion on perfusion computed tomography following revascularization for acute stroke.” Acta Radiol 46, no. 6 (October 2005): 610–15. https://doi.org/10.1080/02841850510021607.
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    • Wintermark, M., M. Sesay, E. Barbier, K. Borbély, W. P. Dillon, J. D. Eastwood, T. C. Glenn, et al. “Comparative overview of brain perfusion imaging techniques.” Stroke 36, no. 9 (September 1, 2005): 2032–33. https://doi.org/10.1161/01.STR.0000177839.03321.25.
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    • Kealey, Susan M., Todd Aho, David Delong, Daniel P. Barboriak, James M. Provenzale, and James D. Eastwood. “Assessment of apparent diffusion coefficient in normal and degenerated intervertebral lumbar disks: initial experience.” Radiology 235, no. 2 (May 2005): 569–74. https://doi.org/10.1148/radiol.2352040437.
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    • Laslo, Amanda M., James D. Eastwood, Brad Urquhart, Ting-Yim Lee, and Dave Freeman. “Subcutaneous administration of nimodipine improves bioavailability in rabbits.” J Neurosci Methods 139, no. 2 (October 30, 2004): 195–201. https://doi.org/10.1016/j.jneumeth.2004.04.030.
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    • Sanelli, Pina C., Michael H. Lev, James D. Eastwood, R Gilberto Gonzalez, and Ting Y. Lee. “The effect of varying user-selected input parameters on quantitative values in CT perfusion maps.” Acad Radiol 11, no. 10 (October 2004): 1085–92. https://doi.org/10.1016/j.acra.2004.07.002.
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    • Galvez, Marcello, Gerald E. York, and James D. Eastwood. “CT perfusion parameter values in regions of diffusion abnormalities.” Ajnr Am J Neuroradiol 25, no. 7 (August 2004): 1205–10.
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    • Kealey, Susan M., Vilert A. Loving, David M. Delong, and James D. Eastwood. “User-defined vascular input function curves: influence on mean perfusion parameter values and signal-to-noise ratio.” Radiology 231, no. 2 (May 2004): 587–93. https://doi.org/10.1148/radiol.2312030489.
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    • Wellons, John C., Ali R. Zomorodi, Alan T. Villaviciencio, Christopher W. Woods, William T. Lawson, and James D. Eastwood. “Sacral tuberculosis: a case report and review of the literature.” Surg Neurol 61, no. 2 (February 2004): 136–39. https://doi.org/10.1016/s0090-3019(03)00265-9.
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    • Eastwood, James D., Michael H. Lev, Max Wintermark, Clemens Fitzek, Daniel P. Barboriak, David M. Delong, Ting-Yim Lee, et al. “Correlation of early dynamic CT perfusion imaging with whole-brain MR diffusion and perfusion imaging in acute hemispheric stroke.” Ajnr Am J Neuroradiol 24, no. 9 (October 2003): 1869–75.
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    • Eastwood, J. D., and J. M. Provenzale. “Cerebral blood flow, blood volume, and vascular permeability of cerebral glioma assessed with dynamic CT perfusion imaging.” Neuroradiology 45, no. 6 (June 2003): 373–76. https://doi.org/10.1007/s00234-003-0996-y.
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    • Eastwood, James D., Stefan T. Engelter, James F. MacFall, David M. Delong, and James M. Provenzale. “Quantitative assessment of the time course of infarct signal intensity on diffusion-weighted images.” Ajnr Am J Neuroradiol 24, no. 4 (April 2003): 680–87.
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    • Eastwood, James D., Michael H. Lev, and James M. Provenzale. “Perfusion CT with iodinated contrast material.” Ajr Am J Roentgenol 180, no. 1 (January 2003): 3–12. https://doi.org/10.2214/ajr.180.1.1800003.
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    • Johnston, Dean C. C., James D. Eastwood, Thanh Nguyen, and Larry B. Goldstein. “Contrast-enhanced magnetic resonance angiography of carotid arteries: utility in routine clinical practice.” Stroke 33, no. 12 (December 2002): 2834–38. https://doi.org/10.1161/01.str.0000043632.51378.24.
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    • Eastwood, James D., Chad A. Holder, Patricia A. Hudgins, and Allen W. Song. “Magnetic resonance imaging with lateralized arterial spin labeling.” Magn Reson Imaging 20, no. 8 (October 2002): 583–86. https://doi.org/10.1016/s0730-725x(02)00536-2.
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    • Turner, Christopher D., Sridharan Gururangan, James Eastwood, Krystal Bottom, Melody Watral, Rodney Beason, Roger E. McLendon, et al. “Phase II study of irinotecan (CPT-11) in children with high-risk malignant brain tumors: the Duke experience.” Neuro Oncol 4, no. 2 (April 2002): 102–8. https://doi.org/10.1093/neuonc/4.2.109.
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    • Eastwood, James D., Robin T. Vollmer, and James M. Provenzale. “Diffusion-weighted imaging in a patient with vertebral and epidural abscesses.” Ajnr Am J Neuroradiol 23, no. 3 (March 2002): 496–98.
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    • Eastwood, James D., Michael J. Alexander, Jeffrey R. Petrella, and James M. Provenzale. “Dynamic CT perfusion imaging with acetazolamide challenge for the preprocedural evaluation of a patient with symptomatic middle cerebral artery occlusive disease.” Ajnr Am J Neuroradiol 23, no. 2 (February 2002): 285–87.
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    • Eastwood, James D., Michael H. Lev, Tarek Azhari, Ting-Yim Lee, Daniel P. Barboriak, David M. Delong, Clemens Fitzek, et al. “CT perfusion scanning with deconvolution analysis: pilot study in patients with acute middle cerebral artery stroke.” Radiology 222, no. 1 (January 2002): 227–36. https://doi.org/10.1148/radiol.2221010471.
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    • Eastwood, J. D., D. A. Turner, R. E. McLendon, and J. M. Provenzale. “Diffusion-weighted MR imaging in a patient with spinal meningioma.” Ajr Am J Roentgenol 177, no. 6 (December 2001): 1479–81. https://doi.org/10.2214/ajr.177.6.1771479.
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    • Eastwood, J. D., D. J. Fiorella, J. F. MacFall, D. M. Delong, J. M. Provenzale, and R. S. Greenwood. “Increased brain apparent diffusion coefficient in children with neurofibromatosis type 1.” Radiology 219, no. 2 (May 2001): 354–58. https://doi.org/10.1148/radiology.219.2.r01ap25354.
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    • Eastwood, J. D., J. M. Provenzale, L. M. Hurwitz, and T. Y. Lee. “Practical injection-rate CT perfusion imaging: deconvolution-derived hemodynamics in a case of stroke.” Neuroradiology 43, no. 3 (March 2001): 223–26. https://doi.org/10.1007/s002340000528.
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    • Lee, E. R., and J. D. Eastwood. “An unusual variant of the fronto-orbital artery.” Ajnr Am J Neuroradiol 21, no. 5 (May 2000): 939–40.
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    • Holder, C. A., R. Muthupillai, S. Mukundan, J. D. Eastwood, and P. A. Hudgins. “Diffusion-weighted MR imaging of the normal human spinal cord in vivo.” Ajnr Am J Neuroradiol 21, no. 10 (2000): 1799–1806.
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    • Eastwood, J. D., and P. A. Hudgins. “New techniques in magnetic resonance imaging.” Curr Opin Ophthalmol 9, no. 6 (December 1998): 54–60. https://doi.org/10.1097/00055735-199812000-00009.
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    • Eastwood, J. D., P. A. Hudgins, and D. Malone. “Retropharyngeal effusion in acute calcific prevertebral tendinitis: diagnosis with CT and MR imaging.” Ajnr Am J Neuroradiol 19, no. 9 (October 1998): 1789–92.
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    • Eastwood, J. D. “Imaging diagnosis of vascular anomalies of the head and neck.” Applied Radiology 25, no. SUPPL. (December 1, 1996): 74–78.
    • Eastwood, J. D., and B. L. Dolmatch. “Percutaneous ureteral biopsy with the Simpson atherectomy catheter.” J Vasc Interv Radiol 7, no. 2 (1996): 253–54. https://doi.org/10.1016/s1051-0443(96)70772-8.
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  • Book Sections

    • Kealey, S. M., and J. D. Eastwood. “Practical approach to CT perfusion scan analysis for the physician.” In Multidetector Computed Tomography in Cerebrovascular Disease: CT Perfusion Imaging, 121–37, 2007.
• Teaching & Mentoring
• 

  Recent Courses

  • RADIOL 421C: Clerkship in Neuroradiology 2023
  • RADIOL 421C: Clerkship in Neuroradiology 2022
  • RADIOL 421C: Clerkship in Neuroradiology 2021

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