Postoperative radiotherapy of the prostate for patients undergoing radical prostatectomy with positive margins, seminal vesicle involvement and/or penetration through the capsule.


Journal Article

A group of 159 patients previously reported as having margins positive for disease after radical prostatectomy with or without adjunctive postoperative radiation was reanalyzed to determine whether the reported benefit did indeed exist. Upon re-examination of the 159 patients 15 were identified who did not receive radical prostatectomy but who were analyzed as if they had received this therapy. An updated review of the total pool of 159 patients with analysis as to failure, death of any cause or death of prostatic cancer demonstrated no benefit of postoperative radiation therapy for margin positive disease. Exclusion of patients who did not receive radical prostatectomy and analysis as described also failed to identify any benefit of postoperative adjunctive radiation therapy.

Full Text

Duke Authors

Cited Authors

  • Paulson, DF; Moul, JW; Robertson, JE; Walther, PJ

Published Date

  • June 1, 1990

Published In

Volume / Issue

  • 143 / 6

Start / End Page

  • 1178 - 1182

PubMed ID

  • 2342178

Pubmed Central ID

  • 2342178

International Standard Serial Number (ISSN)

  • 0022-5347

Digital Object Identifier (DOI)

  • 10.1016/s0022-5347(17)40219-9


  • eng

Conference Location

  • United States