Skip to main content
Journal cover image

Factors predicting early and late phase decline of sexual health-related quality of life following radical prostatectomy.

Publication ,  Journal Article
Kimura, M; Bañez, LL; Schroeck, FR; Gerber, L; Qi, J; Satoh, T; Baba, S; Robertson, CN; Walther, PJ; Donatucci, CF; Moul, JW; Polascik, TJ
Published in: J Sex Med
October 2011

INTRODUCTION: The association between early and late phase sexual health-related quality of life (HRQoL) following radical prostatectomy (RP) is unclear. Moreover, factors that predict either early or late sexual HRQoL decline have not been fully investigated. AIM: The aim of this study was to evaluate the correlation between early and late phase sexual HRQoL decline, and identify clinical parameters that predict substantial sexual HRQoL decline after surgery in the early phase (3 months) and late phase (20 months) following RP. METHODS: We analyzed data on 2,345 consecutive patients who underwent radical retropubic prostatectomy, radical perineal prostatectomy, or robotic-assisted laparoscopic prostatectomy between 2001 and 2009 from the Duke Prostate Center database. MAIN OUTCOME MEASURE: Sexual HRQoL was assessed using the Expanded Prostate Cancer Index Composite instrument at baseline, early and late phase after surgery. The Spearman rank test was used to calculate correlation coefficients between early and late phase sexual HRQoL decline. Logistic regression analysis was performed to identify factors associated with substantial sexual HRQoL decline during both phases. RESULTS: Of 406 men who met our criteria, 217 (53.5%) men had normal erectile function, whereas 189 (46.5%) men had erectile dysfunction at baseline. Declines of sexual HRQoL during early phase had a significant association with that of a decline during late phase (r = 0.48, P < 0.001). In logistic regression, older age at surgery (odds ratio [OR], 1.06; P = 0.007 and OR, 1.08; P = 0.001), African-American race (OR, 4.32; P = 0.001 and OR, 3.13; P = 0.017), and overall comorbidity (OR, 1.43; P = 0.072 and OR, 1.72; P = 0.010) were consistently associated with substantial decline of sexual HRQoL in both early and late phases. CONCLUSIONS: Sexual HRQoL at early and late phases after RP were strongly correlated. Additionally, several factors were identified to be a predictor for decline of sexual HRQoL. Our findings may be used to advise patients who possess aforementioned risk factors during both phases.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

J Sex Med

DOI

EISSN

1743-6109

Publication Date

October 2011

Volume

8

Issue

10

Start / End Page

2935 / 2943

Location

Netherlands

Related Subject Headings

  • Time Factors
  • Surveys and Questionnaires
  • Sexual Behavior
  • Retrospective Studies
  • Racial Groups
  • Quality of Life
  • Prostatic Neoplasms
  • Prostatectomy
  • Obstetrics & Reproductive Medicine
  • Middle Aged
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Kimura, M., Bañez, L. L., Schroeck, F. R., Gerber, L., Qi, J., Satoh, T., … Polascik, T. J. (2011). Factors predicting early and late phase decline of sexual health-related quality of life following radical prostatectomy. J Sex Med, 8(10), 2935–2943. https://doi.org/10.1111/j.1743-6109.2011.02387.x
Kimura, Masaki, Lionel L. Bañez, Florian R. Schroeck, Leah Gerber, Jim Qi, Takefumi Satoh, Shiro Baba, et al. “Factors predicting early and late phase decline of sexual health-related quality of life following radical prostatectomy.J Sex Med 8, no. 10 (October 2011): 2935–43. https://doi.org/10.1111/j.1743-6109.2011.02387.x.
Kimura M, Bañez LL, Schroeck FR, Gerber L, Qi J, Satoh T, et al. Factors predicting early and late phase decline of sexual health-related quality of life following radical prostatectomy. J Sex Med. 2011 Oct;8(10):2935–43.
Kimura, Masaki, et al. “Factors predicting early and late phase decline of sexual health-related quality of life following radical prostatectomy.J Sex Med, vol. 8, no. 10, Oct. 2011, pp. 2935–43. Pubmed, doi:10.1111/j.1743-6109.2011.02387.x.
Kimura M, Bañez LL, Schroeck FR, Gerber L, Qi J, Satoh T, Baba S, Robertson CN, Walther PJ, Donatucci CF, Moul JW, Polascik TJ. Factors predicting early and late phase decline of sexual health-related quality of life following radical prostatectomy. J Sex Med. 2011 Oct;8(10):2935–2943.
Journal cover image

Published In

J Sex Med

DOI

EISSN

1743-6109

Publication Date

October 2011

Volume

8

Issue

10

Start / End Page

2935 / 2943

Location

Netherlands

Related Subject Headings

  • Time Factors
  • Surveys and Questionnaires
  • Sexual Behavior
  • Retrospective Studies
  • Racial Groups
  • Quality of Life
  • Prostatic Neoplasms
  • Prostatectomy
  • Obstetrics & Reproductive Medicine
  • Middle Aged